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抗Mouse (Murine) GNB3 抗体:
抗Human GNB3 抗体:
抗Rat (Rattus) GNB3 抗体:
Human Polyclonal GNB3 Primary Antibody for ELISA, IHC - ABIN4315238
Gentile, Missori, Borro, Sebastianelli, Simmaco, Martelletti: Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine. in The journal of headache and pain 2010
Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia.
A transgenic model carries an extra copy of GNB3, weighs significantly more than wild-type littermates, and has excess fat accumulation. GNB3 is highly expressed in the brain, consistent with G-protein signaling involved in satiety and/or metabolism.
These results suggest that the main role of Gbeta3 in cones is to establish optimal levels of transducin (显示 GNAT1 抗体) heteromer in the outer segment, thereby indirectly contributing to robust response properties.
The results of this study showed that Gbeta (显示 SUCLG2 抗体)(3) may play a role in synaptic maintenance since in its absence, the number of invaginating rod bipolar dendrites is greatly reduced, a deficit that was not observed at 3 weeks, the end of the developmental period.
Gbeta3 subunit is coexpressed in physiologically ON-type cone bipolar cells with Ggamma13 (显示 GNg13 抗体) and Gbeta4 but is not present in OFF-type bipolar cells.
Our results demonstrate the potential use of a GNB3-specific antisense morpholino, as a pharmacogenetic therapy for essential hypertension
No relationship was found between the studied polymorphisms (14094 ACE (显示 ACE 抗体) gene, rs1800469 gene TGFbeta1 (显示 TGFB1 抗体), GNB3 gene rs5443, rs5186 AGTR1 (显示 AGTR1 抗体) gene) and the occurrence of primary vesicoureteral reflux. TT genotype polymorphism rs5443 of the GNB3 gene may be a protective factor for improved renal function in patients with primary vesicoureteral reflux.
Interactions between GNB3, CREB1 (显示 CREB1 抗体) and negative life events were revealed. Further evidence is provided about the role of the environment in genetic vulnerability to major depression.
Bipolar patients with the TT genotype had a lower BMI, smaller waist circumference, and lower levels of lipids and leptin (显示 LEP 抗体) than those with the CT or CC genotypes undergoing the valproic acid treatment course.
Mutational analysis of GNB3 in a cohort of 58 subjects with CSNB (显示 CSN2 抗体) identified a sporadic case individual with a homozygous GNB3 mutation
The GNB3 TT genotype is a risk factor for coronary artery disease independent of other established cardiovascular risk factors in Chinese hypertensive patients.
The combined effects of ACE (显示 ACE 抗体) and GNB3 polymorphisms showed that no pulmonary hypertension patients with the ACE (显示 ACE 抗体)/GNB3 II/TT genotype exhibited clinical worsening.
Although not statistically significant, women who carried the GNB3 T risk allele gained 6 pounds more than noncarriers, and mean 6-month postpartum BMI differed by 2.2 kg/m(2) between homozygous women
GNB3 C825T polymorphisms may be correlated with the efficacy of antidepressants in the treatment of MDD, especially among Asians patients.
GNB3 TT genotype was associated with lower left ventricular ejection fraction at 6 and 12 months in women with peripartum cardiomyopathy.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
guanine nucleotide binding protein (G protein), beta polypeptide 3
, Transducin beta chain 3
, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
, guanine nucleotide binding protein, beta 3
, transducin beta chain 3
, G protein, beta-3 subunit
, GTP-binding regulatory protein beta-3 chain
, guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
, hypertension associated protein
, GTP-binding protein beta-3 subunit short isoform
, transducin beta-3-subunit
, G protein beta-subunit
, guanine nucleotide binding protein (G protein), beta 3
, guanine nucleotide-binding protein, beta-3 subunit