anti-小鼠 SERPINE1 抗体 for Immunoprecipitation

Recommended SERPINE1 Antibody (supplied by: Log in to see )

抗原
serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) 抗体
  • PAI
  • PAI-1
  • PAI1
  • PLANH1
  • SERPINE1
  • si:ch211-138a11.1
  • Planh1
  • PAI1A
  • Pai1
  • Pai1aa
  • Planh
  • RATPAI1A
  • serpin family E member 1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • serine (or cysteine) peptidase inhibitor, clade E, member 1
  • SERPINE1
  • serpine1.L
  • serpine1
  • Serpine1
适用
小鼠, 人
431
130
121
38
12
10
7
6
5
4
3
2
2
1
1
宿主

276
184
54
26
2
1
1
克隆类型
多克隆
标记
This SERPINE1 antibody is un-conjugated
51
35
21
7
7
5
5
5
5
5
5
5
5
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
1
应用范围
Immunoprecipitation (IP), Western Blotting (WB)
395
279
222
69
39
33
30
29
26
22
20
19
18
10
6
5
5
4
4
4
2
1
1
1
1
选项
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产品编号 ABIN5663865
$ 411.13
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2920446 IF/ICC IHC IP WB Rabbit AA 141-389 Log in to see Polyclonal 0
1 ABIN5702299 ELISA IHC IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6034116 IF/ICC IHC IP WB Rabbit Log in to see Polyclonal 0
1 ABIN5914700 ELISA IHC IP WB Rabbit IgG Log in to see Polyclonal 0

General

抗原 serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) 抗体
适用 小鼠, 人
(431), (130), (121), (38), (12), (10), (7), (6), (5), (4), (3), (2), (2), (1), (1)
宿主
(276), (184), (54), (26), (2), (1), (1)
克隆类型
多克隆
标记 This SERPINE1 antibody is un-conjugated
(51), (35), (21), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
应用范围 Immunoprecipitation (IP), Western Blotting (WB)
(395), (279), (222), (69), (39), (33), (30), (29), (26), (22), (20), (19), (18), (10), (6), (5), (5), (4), (4), (4), (2), (1), (1), (1), (1)
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SERPINE1抗体详情

SERPINE1目标详情 使用细节 贮存及处理 图像
纯化方法 Affinity purification
免疫原 A synthetic peptide of human PAI-1
亚型 IgG
Plasmids, Primers & others

SERPINE1目标详情

SERPINE1抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 PAI-1 (SERPINE1 Antibody 摘要)
背景 PAI-1 is a secreted protein that belongs to the serine proteinase inhibitor (serpin) superfamily. It inhibits urokinase and tissue plasminogen activators (uPA and tPA) and thus, reduces the conversion of inactive plasminogen to plasmin. PAI-1 regulates fibrinolysis and plays an important role in vessel patency and tissue remodeling. Secreted PAI-1 interacts with the extracellular matrix (ECM) component vitronectin, thereby modulating cell-ECM interactions. PAI-1 is expressed in a variety of tissues with higher expression in liver, vascular endothelial cells, platelets, macrophages, and adipose tissue. Increased levels of PAI-1 are associated with deep vein thrombosis. Defects in PAI-1 cause plasminogen activator inhibitor-1 deficiency (PAI-1D), which is characterized by increased bleeding after injury or surgery. Research studies have shown that high levels of PAI-1 are associated with obesity, aging, insulin resistance, and type 2 diabetes. PAI-1 is transcriptionally regulated by TGF-beta and mediates TGF-beta-induced inhibition of cell migration and invasion in cancer cells. Studies have shown PAI-1 to be also involved in fibrosis.
Synonyms: SERPINE1, PAI, PAI-1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1
基因ID 5054
UniProt P05121
途径 p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration

使用细节

SERPINE1抗体详情 SERPINE1目标详情 贮存及处理 图像 回页首
应用备注 Recommended dilutions: WB: 1:500-1:2000, IP: 1:20-1:50
限制 仅限研究用

贮存及处理

SERPINE1抗体详情 SERPINE1目标详情 使用细节 图像 回页首
状态 Liquid
缓冲液 PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid freeze / thaw cycles
储存条件 -20 °C/-80 °C

图像

SERPINE1抗体详情 SERPINE1目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) antibody (ABIN5663865) Western blot analysis of extracts of various cell lines, using PAI-1 antibody.