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CHEK1 抗体

(Checkpoint Kinase 1 (CHEK1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
CHEK1 抗体  (pSer280) CHEK1 抗体  (pSer280) CHEK1 抗体 (pSer280) (ABIN6255160)

CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

CHEK1 抗体  (pSer317) CHEK1 抗体  (pSer317) CHEK1 抗体 (pSer317) (ABIN6255201)

CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

CHEK1 抗体  (pSer286) CHEK1 抗体  (pSer286) CHEK1 抗体 (pSer286) (ABIN6255167)

CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

CHEK1 抗体 by Grade

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CHEK1 抗体 by 适用

Find CHEK1 抗体 for a variety of species such as anti-Human CHEK1, anti-Mouse CHEK1, anti-Rat CHEK1. The species listed below are among those available. Click on a link to go to the corresponding products.

CHEK1 抗体 by 应用范围

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CHEK1 抗体 by 抗体来源

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CHEK1 抗体 by 抗原表位

Find CHEK1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CHEK1 抗体 by 克隆形成能力

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CHEK1 抗体 by 克隆

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CHEK1 抗体 by 标记

Find CHEK1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CHEK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (12)
Cat. No. ABIN6255160
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (10)
Cat. No. ABIN6255201
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (7)
Cat. No. ABIN6255167
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (8)
Cat. No. ABIN6256255
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (12)
Cat. No. ABIN6256251
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7263651
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN2857048
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7265022
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN2779737
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Mouse
Application ELISA, IHC (p), IF (p), ICC, IF (cc), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN757072
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7127424
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN969476
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7138533
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7138530
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6241016
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CHEK1 抗体

Fu, Sun, Xia, Hobbs, Guo, Coulombe, Wan: "Sam68 is required for the growth and survival of nonmelanoma skin cancer." in: Cancer medicine, Vol. 8, Issue 13, pp. 6106-6113, (2019) (PubMed).

Bai, Wang, Huo, Xie, Xie, Xu, Wang: "Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma." in: Translational oncology, Vol. 11, Issue 1, pp. 140-146, (2018) (PubMed).

Ji, Zheng, Liu, Ren, Gao, Zhang, Li: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." in: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).

Jiang, Wang, Xing, Shen, Lian, Yi, Zhang, Yang, Liu, Zhang: "Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro." in: Archives of toxicology, Vol. 91, Issue 1, pp. 259-270, (2017) (PubMed).

Shibata, Kiran, Shibata, Singh, Kiran, Dutta: "Two subunits of human ORC are dispensable for DNA replication and proliferation." in: eLife, Vol. 5, (2017) (PubMed).

Xu, Zhou, Xiong, Zou, Deng, Ganaie, Kleiboeker, Peng, Liu, Wang, Ye, Qiu: "Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway." in: PLoS pathogens, Vol. 13, Issue 3, pp. e1006266, (2017) (PubMed).

Awate, De Benedetti: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." in: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).

Chang, Chan, R McGhie, Udugama, Mayne, Collas, Mann, Wong: "CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells." in: Nucleic acids research, Vol. 43, Issue 5, pp. 2603-14, (2015) (PubMed).

Guo, Cui, Peng, Fang, Zuo, Deng, Wang, Wu, Chen, Deng: "Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney." in: Oncotarget, Vol. 6, Issue 34, pp. 35964-77, (2015) (PubMed).

Yun, Shi, Yang, Zhang, Wang, Zhou, Mu: "Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy." in: Scientific reports, Vol. 4, pp. 7548, (2015) (PubMed).

Aliases for CHEK1 抗体

checkpoint kinase 1 (CHEK1) 抗体
serine/threonine-protein kinase chk1 (ANI_1_2436074) 抗体
serine/threonine-protein kinase chk1 (AOR_1_768154) 抗体
serine/threonine-protein kinase Chk1 (PTRG_04183) 抗体
CAMK/CAMKL/CHK1 protein kinase Chk1 (SJAG_01680) 抗体
serine/threonine-protein kinase chk1 (PAAG_04978) 抗体
serine/threonine-protein kinase chk1 (MCYG_03290) 抗体
serine/threonine-protein kinase chk1 (VDBG_03742) 抗体
checkpoint kinase 1 S homeolog (chek1.S) 抗体
checkpoint kinase 1 (Chek1) 抗体
checkpoint kinase 1 (chek1) 抗体
An08g10320 抗体
AO090003000441 抗体
C85740 抗体
CHEK1 抗体
CHK1 抗体
chk1 抗体
Chk1 抗体
id:ibd2720 抗体
rad27 抗体
zgc:56093 抗体
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