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|抗原||V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) 抗体|
|标记||This C-MYC antibody is un-conjugated 其他选择|
Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
|Supplier||Log in to see|
C-MYC抗体详情C-MYC目标详情 使用细节 贮存及处理 图像
|纯化方法||Purified by Protein A.|
|免疫原||Synthetic peptide derived from human c-Myc(S62), around 50-100aa (phospho S62).|
C-MYC目标详情C-MYC抗体详情 使用细节 贮存及处理 图像 回页首
|别名||c-Myc (MYC Antibody 摘要)|
Epitope tags are useful for the labeling and detection of proteins usingimmunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged protein's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast,insect and mammalian cell systems.The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Synonyms: Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, c Myc Epitope Tag, c Myc Tag, Cellular myelocytomatosis oncogene, MGC105490, MRTL, Myc Epitope Tag, Myc protein, Myc proto oncogene protein, Myc proto-oncogene protein, Myc-related translation/localization regulatory factor, Myc2, myca, Myelocytomatosis oncogene a, Myelocytomatosis oncogene, Niard, Nird, Oncogene Myc, Protooncogene homologous to myelocytomatosis virus, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, V-Myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog avian, zc-myc.
|途径||p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus|
使用细节C-MYC抗体详情 C-MYC目标详情 贮存及处理 图像 回页首
贮存及处理C-MYC抗体详情 C-MYC目标详情 使用细节 图像 回页首
|缓冲液||Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.|
|储存方法||Store at -20°C|
图像C-MYC抗体详情 C-MYC目标详情 使用细节 贮存及处理 回页首