anti-人 C-MYC 抗体 for Fluorescence Microscopy

Recommended C-MYC Antibody (supplied by: Log in to see )

抗原
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) 抗体
  • MRTL
  • MYCC
  • bHLHe39
  • c-Myc
  • CMYC
  • c-myc
  • C-MYC
  • LOC100136746
  • RNCMYC
  • mMyc
  • AU016757
  • Myc2
  • Niard
  • Nird
  • MYC
  • cmyc
  • zc-myc
  • c-myc II
  • myc-B
  • myc2
  • CMyc
  • CG10798
  • D-Myc
  • DM
  • DMYc
  • Dm
  • Dmel\CG10798
  • Dmyc
  • EG:BACN5I9.1
  • anon-WO03040301.171
  • bHLHe57
  • c-MYC
  • d-myc
  • dMYC
  • dMyc
  • dMyc1
  • da
  • dm
  • dm/dMyc
  • dm/myc
  • dmyc
  • dmyc1
  • l(1)G0139
  • l(1)G0354
  • l(1)G0359
  • myc
  • MYC proto-oncogene, bHLH transcription factor
  • v-myc myelocytomatosis viral oncogene homolog
  • myelocytomatosis oncogene
  • MYC proto-oncogene, bHLH transcription factor a
  • MYC proto-oncogene, bHLH transcription factor L homeolog
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • CG10798 gene product from transcript CG10798-RB
  • MYC
  • LOC100136746
  • Myc
  • myca
  • myc.L
适用

693
212
120
50
42
36
20
20
19
14
14
13
12
9
9
6
6
5
4
4
4
3
3
2
1
1
1
1
1
宿主
小鼠
371
337
28
16
8
1
克隆类型
单克隆
标记
This C-MYC antibody is un-conjugated
47
40
39
21
18
17
17
14
13
13
13
13
13
13
12
12
12
10
5
5
5
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
应用范围
Fluorescence Microscopy (FM), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
477
245
227
226
224
192
152
122
91
52
18
14
14
11
10
8
6
6
2
2
1
1
选项
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产品编号 ABIN967320
产品在该地区无法提供。
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN967319 FM IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 9E10 13

General

抗原 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) 抗体
适用
(693), (212), (120), (50), (42), (36), (20), (20), (19), (14), (14), (13), (12), (9), (9), (6), (6), (5), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1)
宿主 小鼠
(371), (337), (28), (16), (8), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This C-MYC antibody is un-conjugated
(47), (40), (39), (21), (18), (17), (17), (14), (13), (13), (13), (13), (13), (13), (12), (12), (12), (10), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
应用范围 Fluorescence Microscopy (FM), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(477), (245), (227), (226), (224), (192), (152), (122), (91), (52), (18), (14), (14), (11), (10), (8), (6), (6), (2), (2), (1), (1)
Pubmed 13个引用可参考
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C-MYC抗体详情

C-MYC目标详情 使用细节 贮存及处理 References for anti-C-MYC antibody (ABIN967320) 图像
品牌 BD Pharmingen™
产品特性 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Human c-Myc Peptide
克隆位点 9E10
亚型 IgG1

C-MYC目标详情

C-MYC抗体详情 使用细节 贮存及处理 References for anti-C-MYC antibody (ABIN967320) 图像 回页首
抗原
别名 c-Myc (MYC Antibody 摘要)
背景 The myc gene family contains at least seven closely related genes, c-myc, N-myc, L-myc, P-myc, R-myc, S-myc, and B-myc. C-myc plays a role in proliferation, transformation, and differentiation. It is expressed during embryonic development, in a wide variety of adult tissues, and is amplified in many tumors, particularly lung, breast, cervical and colon carcinomas. Cellular localization has been described as nuclear and/or cytopasmic. C-myc has three sequence motifs in the carboxy terminus, a leucine zipper, a helix-loop-helix, and a basic region. It forms sequence-specific (CACGTG) DNA binding heterodimers with max, a helixloop-helix/leucine zipper protein. Both the leucine zipper domain and the helixloop-helix motif of c-myc contribute to heterodimer formation. DNA binding of myc-max dimers results in a conformational change of the DNA and transcriptional activation. C-myc migrates at 62 kDa in SDS-PAGE. Clone 9E10 recognizes human c-myc. A synthetic peptide corresponding to a C-terminal epitope of the human c-myc protein (AEEQKLISEEDL) was used as an immunogen.
途径 p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

使用细节

C-MYC抗体详情 C-MYC目标详情 贮存及处理 References for anti-C-MYC antibody (ABIN967320) 图像 回页首
应用备注 It is particularly useful for western blot analysis of myc-tagged recombinant proteins, and recombinant c-myc. Jurkat control lysate [50 µg (1 µg/µl)] is provided as a western blot positive control (store lysate at -20 °C). Additional control lysate is sold separately.
说明

Related Products: ABIN968537, ABIN967389

限制 仅限研究用

贮存及处理

C-MYC抗体详情 C-MYC目标详情 使用细节 References for anti-C-MYC antibody (ABIN967320) 图像 回页首
状态 Liquid
浓度 1.0 mg/mL
缓冲液 Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store undiluted at -20° C.

References for anti-C-MYC antibody (ABIN967320)

C-MYC抗体详情 C-MYC目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Liu, Hsu, Goeddel, Karin: "Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death." in: Cell, Vol. 87, Issue 3, pp. 565-76, 1996

Lukas, Parry, Aagaard, Mann, Bartkova, Strauss, Peters, Bartek: "Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16." in: Nature, Vol. 375, Issue 6531, pp. 503-6, 1995

Royds, Sharrard, Wagner, Polacarz: "Cellular localisation of c-myc product in human colorectal epithelial neoplasia." in: The Journal of pathology, Vol. 166, Issue 3, pp. 225-33, 1992

Tosca, Linardopoulos, Malliri, Hatziolou, Nicolaidou, Spandidos: "Implication of the ras and myc oncoproteins in the pathogenesis of mycosis fungoides." in: Anticancer research, Vol. 11, Issue 4, pp. 1433-8, 1992

Blackwood, Eisenman: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." in: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, 1991

DePinho, Schreiber-Agus, Alt: "myc family oncogenes in the development of normal and neoplastic cells." in: Advances in cancer research, Vol. 57, pp. 1-46, 1991

Gosney, Field, Gosney, Lye, Spandidos, Butt: "c-myc oncoprotein in bronchial carcinoma: expression in all major morphological types." in: Anticancer research, Vol. 10, Issue 3, pp. 623-8, 1990

Karayiannis, Yiagnisis, Papadimitriou, Field, Spandidos: "Evaluation of the ras and myc oncoproteins in benign gastric lesions." in: Anticancer research, Vol. 10, Issue 5A, pp. 1127-33, 1990

Spandidos, Yiagnisis, Papadimitriou, Field: "ras, c-myc and c-erbB-2 oncoproteins in human breast cancer." in: Anticancer research, Vol. 9, Issue 5, pp. 1385-93, 1990

Evan, Lewis, Ramsay, Bishop: "Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product." in: Molecular and cellular biology, Vol. 5, Issue 12, pp. 3610-6, 1986

背景

Campbell, Kessler, Fambrough: "The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca(2+)-ATPases are on opposite sides of the membrane." in: The Journal of biological chemistry, Vol. 267, Issue 13, pp. 9321-5, 1992

Williams, Piris, Wyllie: "Immunohistochemical demonstration of altered intracellular localization of the C-Myc oncogene product in human colorectal neoplasms." in: The Journal of pathology, Vol. 160, Issue 4, pp. 287-93, 1990

Tiniakos, Spandidos, Kakkanas, Pintzas, Pollice, Tiniakos: "Expression of ras and myc oncogenes in human hepatocellular carcinoma and non-neoplastic liver tissues." in: Anticancer research, Vol. 9, Issue 3, pp. 715-21, 1989

图像

C-MYC抗体详情 C-MYC目标详情 使用细节 贮存及处理 References for anti-C-MYC antibody (ABIN967320) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) antibody (ABIN967320) Western blot analysis of c-myc. Lysate from Jurkat cells was probed with anti-c-myc (...