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APAF1 抗体

(Apoptotic Peptidase Activating Factor 1 (APAF1))
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
APAF1 抗体  (AA 1-250) APAF1 抗体  (AA 1-250) APAF1 抗体 (AA 1-250) (ABIN1678685)

APAF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

APAF1 抗体  (AA 31-350) APAF1 抗体  (AA 31-350) APAF1 抗体 (AA 31-350) (ABIN7433081)

APAF1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

APAF1 抗体  (AA 1138-1237) APAF1 抗体  (AA 1138-1237) APAF1 抗体 (AA 1138-1237) (ABIN5611196)

APAF1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2H9A1 unconjugated

APAF1 抗体 by 适用

Find APAF1 抗体 for a variety of species such as anti-Human APAF1, anti-Rat APAF1, anti-Mouse APAF1. The species listed below are among those available. Click on a link to go to the corresponding products.

APAF1 抗体 by 应用范围

Find APAF1 抗体 validated for a specific application such as WB, IF (cc), ELISA, IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

APAF1 抗体 by 抗体来源

Find APAF1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

APAF1 抗体 by 抗原表位

Find APAF1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APAF1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal APAF1 抗体. Click on a link to go to the corresponding products.

APAF1 抗体 by 克隆

Find APAF1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

APAF1 抗体 by 标记

Find APAF1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APAF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (7)
Cat. No. ABIN1678685
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (5)
Cat. No. ABIN7433081
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (5)
Cat. No. ABIN5611196
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validations
  • (3)
Cat. No. ABIN724310
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat, Zebrafish (Danio rerio)
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN724295
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7144485
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6259968
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7184575
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN513376
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN534446
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7294924
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN513375
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
Cat. No. ABIN2477457
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, IP
Validations
  • (3)
Cat. No. ABIN2745510
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN2854918
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our APAF1 抗体

Oladzad, Nikkhah, Hosseinkhani: "Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells." in: Sensors (Basel, Switzerland), Vol. 20, Issue 6, (2020) (PubMed).

Tashakor, H-Dehkordi, OConnell, Gomez Ganau, Gozalbes, Eriksson, Hosseinkhani, Fearnhead: "A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation." in: FEBS open bio, Vol. 9, Issue 7, pp. 1194-1203, (2020) (PubMed).

Noori, Hosseini, Nikkhah, Hosseinkhani: "Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems." in: Archives of biochemistry and biophysics, Vol. 642, pp. 46-51, (2019) (PubMed).

Wang, Zhang, Li, Wang, Tong, Wang, Liu, Su, Tu, Zhang, Li: "LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1." in: Acta pharmacologica Sinica, Vol. 38, Issue 7, pp. 1009-1023, (2018) (PubMed).

Rodić, Steranka, Makohon-Moore, Moyer, Shen, Sharma, Kohutek, Huang, Ahn, Mita, Taylor, Barker, Hruban, Iacobuzio-Donahue, Boeke, Burns: "Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma." in: Nature medicine, Vol. 21, Issue 9, pp. 1060-4, (2015) (PubMed).

Kim, Lee, Park, Chung, Im, Noh, Han, Moon, Jung, Ryu: "Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 5, pp. 563-70, (2015) (PubMed).

Shi, Che, Liu et al.: "Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).

Morikawa, Nagahiro, Endo, Sato, Nakashima, Takatani, Mitsumori: "[Intralobar sequestration in elderly patient, report of a case]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 9, pp. 812-5, (2008) (PubMed).

Bao, Lu, Rabinowitz, Shi: "Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1." in: Molecular cell, Vol. 25, Issue 2, pp. 181-92, (2007) (PubMed).

Shi: "Mechanical aspects of apoptosome assembly." in: Current opinion in cell biology, Vol. 18, Issue 6, pp. 677-84, (2006) (PubMed).

Aliases for APAF1 抗体

Death-associated APAF1-related killer (Dark) 抗体
apoptotic peptidase activating factor 1 L homeolog (apaf1.L) 抗体
apoptotic peptidase activating factor 1 (apaf1) 抗体
apoptotic peptidase activating factor 1 (APAF1) 抗体
apoptotic peptidase activating factor 1 (Apaf1) 抗体
6230400I06Rik 抗体
anon-53Fa 抗体
Apaf-1 抗体
apaf-1 抗体
APAF-1 抗体
APAF1 抗体
Apaf1 抗体
apaf1 抗体
Apaf1l 抗体
arc 抗体
ARK 抗体
ark 抗体
CED4 抗体
CG6829 抗体
D-Apaf-1 抗体
dapaf 抗体
Dapaf-1 抗体
dAPAF-1 抗体
dApaf-1 抗体
dapaf-1 抗体
dApaf-1/DARK/HAC-1 抗体
Dapaf-1/HAC-1 抗体
dapaf-1L 抗体
dapaf-1S 抗体
dApaf1 抗体
DARK 抗体
Dark 抗体
dArk 抗体
dark 抗体
Dark/Apaf-I 抗体
dark/dapaf-1/hac-1 抗体
Dark/Dapaf-1/HAC1 抗体
Dark/Hac-1/dApaf-1 抗体
dark/hac-1/dapaf-1 抗体
Dark/Hac-1/dApaf1 抗体
Dmel\\CG6829 抗体
fog 抗体
Hac-1 抗体
hac-1 抗体
Hac-1/Dark 抗体
Hac1 抗体
hac1 抗体
l(2)SH0173 抗体
mKIAA0413 抗体
T1 抗体
zgc:136543 抗体
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