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Poly(A) Binding Protein, Cytoplasmic 1 产品

(Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

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This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation\; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010].

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Featured Poly(A) Binding Protein, Cytoplasmic 1 Categories

Poly(A) Binding Protein, Cytoplasmic 1 抗体

High quality antibodies with extensive validation data.

Poly(A) Binding Protein, Cytoplasmic 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Poly(A) Binding Protein, Cytoplasmic 1 抗体

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Reactivity
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Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
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Cat. No. ABIN7269446
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Hamster, Human, Rabbit, Xenopus laevis
Application WB, ELISA, IF, IP, FACS, ICC
Validations
  • (3)
  • (3)
Cat. No. ABIN108538
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
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  • (3)
Cat. No. ABIN704831
Quantity 100 μL
Datasheet Datasheet

Recommended Poly(A) Binding Protein, Cytoplasmic 1 ELISA试剂盒

Product
Reactivity
Analytical Method
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Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6220344
Quantity 96 tests
Datasheet Datasheet

Recommended Poly(A) Binding Protein, Cytoplasmic 1 蛋白

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Source
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Reactivity Human
Source Wheat germ
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  • (1)
  • (1)
Cat. No. ABIN1313849
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124507
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094395
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Poly(A) Binding Protein, Cytoplasmic 1 Products

Chazal, Daguenet, Wendling, Ulryck, Tomasetto, Sargueil, Le Hir: "EJC core component MLN51 interacts with eIF3 and activates translation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 5903-8, (2013) (PubMed).

Massimelli, Majerciak, Kruhlak, Zheng: "Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA." in: Journal of virology, Vol. 87, Issue 1, pp. 243-56, (2012) (PubMed).

Higashi, Tomigahara, Shiraki, Miyata, Mikami, Kimura, Moro, Inagaki, Kaneko: "A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4485-92, (2011) (PubMed).

Gorgoni, Richardson, Burgess, Anderson, Wilkie, Gautier, Martins, Brook, Sheets, Gray: "Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 19, pp. 7844-9, (2011) (PubMed).

Yao, Li, Jung, Lian, Abadal, Han, Fritzler, Chan: "Divergent GW182 functional domains in the regulation of translational silencing." in: Nucleic acids research, Vol. 39, Issue 7, pp. 2534-47, (2011) (PubMed).

Unsworth, Raguz, Edwards, Higgins, Yagüe: "mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 9, pp. 3370-80, (2010) (PubMed).

Hofmann, Casella, Schnölzer, Schlechter, Spring, Franke: "Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules." in: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1388-98, (2006) (PubMed).

Kanno, Sato, Sata, Katano: "Expression of Kaposi's sarcoma-associated herpesvirus-encoded K10/10.1 protein in tissues and its interaction with poly(A)-binding protein." in: Virology, Vol. 352, Issue 1, pp. 100-9, (2006) (PubMed).

Larralde, Smith, Wilkie, Malik, Gray, Clements: "Direct stimulation of translation by the multifunctional herpesvirus ICP27 protein." in: Journal of virology, Vol. 80, Issue 3, pp. 1588-91, (2006) (PubMed).

Sagliocco, Laloo, Cosson, Laborde, Castroviejo, Rosenbaum, Ripoche, Grosset: "The ARE-associated factor AUF1 binds poly(A) in vitro in competition with PABP." in: The Biochemical journal, Vol. 400, Issue 2, pp. 337-47, (2006) (PubMed).

Synonyms and alternative names related to Poly(A) Binding Protein, Cytoplasmic 1

poly(A) binding protein cytoplasmic 1 (PABPC1), poly(A) binding protein, cytoplasmic 1 (Pabpc1), poly(A) binding protein, cytoplasmic 1 S homeolog (pabpc1.S), poly(A) binding protein, cytoplasmic 1 (pabpc1), poly(A) binding protein cytoplasmic 1 like (PABPC1L), poly(A) binding protein, cytoplasmic 1 L homeolog (pabpc1.L), poly(A) binding protein, cytoplasmic 1a (pabpc1a), poly A binding protein, cytoplasmic 1 b (pabpc1b), poly(A) binding protein cytoplasmic 1 (Pabpc1), ePAB, PAB1, pab1, PABP, Pabp, pabp, PABP1, Pabp1, pabp1, pabpc1, PABPC1, PABPC2, pabpc2, PabpI, PABPL1, Pabpl1, wu:fb16a02, wu:fi19b08, wu:fj12d09, wu:fj61f06, zgc:77608, zgc:109879

Protein level used designations for Poly(A) Binding Protein, Cytoplasmic 1

  • poly(A) binding protein, cytoplasmic 2
  • polyadenylate-binding protein 1
  • PABP-1
  • poly A binding protein 1
  • poly(A)-binding protein 1
  • PABP 1
  • PABP 1-A
  • PABP-1-A
  • PABP-A
  • cytoplasmic poly(A)-binding protein 1-A
  • poly(A)-binding protein 1-A
  • polyadenylate-binding protein 1-A
  • xPABP1-A
  • poly(A) binding protein, cytoplasmic 1
  • polyadenylate-binding protein 1-like
  • PABP 1-B
  • PABP-1-B
  • PABP-B
  • cytoplasmic poly(A)-binding protein 1-B
  • poly(A)-binding protein 1-B
  • polyadenylate-binding protein 1-B
  • xPABP1-B
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