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NR1I2 抗体

(Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008].
NR1I2 抗体  (AA 101-150) NR1I2 抗体  (AA 101-150) NR1I2 抗体 (AA 101-150) (ABIN738816)

NR1I2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

NR1I2 抗体  (AA 1-142) NR1I2 抗体  (AA 1-142) NR1I2 抗体 (AA 1-142) (ABIN5542364)

NR1I2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1D12G1 unconjugated

NR1I2 抗体  (C-Term) NR1I2 抗体  (C-Term) NR1I2 抗体 (C-Term) (ABIN6263716)

NR1I2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

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Popular NR1I2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN738816
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (5)
Cat. No. ABIN5542364
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6263716
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (4)
Cat. No. ABIN5542365
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN652618
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Pig
Application WB, ELISA, FACS, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN679598
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN950157
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN563843
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN522319
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7259534
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN335159
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6741564
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3015525
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
  • (2)
Cat. No. ABIN2774988
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (1)
Cat. No. ABIN7438790
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NR1I2 抗体

Huang, Mukherjee, DesMarais, Albanese, Rafti, Draghi Ii, Maher, Khanna, Mani, Matson: "Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis." in: Pediatric research, Vol. 83, Issue 5, pp. 1031-1040, (2018) (PubMed).

Zhou, Li, Wang, Jin, Shi, Wang, Bi: "Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway." in: Scientific reports, Vol. 6, pp. 27876, (2016) (PubMed).

Sehirli, Cetinel, Ozkan, Selman, Tetik, Yuksel, Dulger: "St. John's wort may ameliorate 2,4,6-trinitrobenzenesulfonic acid colitis off rats through the induction of pregnane X receptors and/or P-glycoproteins." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 66, Issue 2, pp. 203-14, (2015) (PubMed).

Sivertsson, Edebert, Palmertz, Ingelman-Sundberg, Neve: "Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation." in: Molecular pharmacology, Vol. 83, Issue 3, pp. 659-70, (2013) (PubMed).

Dou, Zhang, Zhang, Sun, Ding, Chou, Wang, Mani: "Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-?B signaling pathway." in: The Journal of pharmacology and experimental therapeutics, Vol. 345, Issue 3, pp. 473-82, (2013) (PubMed).

Thakur, Arthanari, Yang, Pan, Fan, Breger, Frueh, Gulshan, Li, Mylonakis, Struhl, Moye-Rowley, Cormack, Wagner, Näär: "A nuclear receptor-like pathway regulating multidrug resistance in fungi." in: Nature, Vol. 452, Issue 7187, pp. 604-9, (2008) (PubMed).

Aliases for NR1I2 抗体

nuclear receptor subfamily 1 group I member 2 (NR1I2) 抗体
nuclear receptor subfamily 1, group I, member 2 (Nr1i2) 抗体
nuclear receptor subfamily 1 group I member 2 (Nr1i2) 抗体
nuclear receptor subfamily 1 group I member 2 S homeolog (nr1i2.S) 抗体
nuclear receptor subfamily 1, group I, member 2 (nr1i2) 抗体
BXR 抗体
bxr 抗体
mPXR 抗体
nr1i2 抗体
ONR1 抗体
onr1 抗体
PAR 抗体
PAR1 抗体
PAR2 抗体
PARq 抗体
PRR 抗体
PXR 抗体
PXR.1 抗体
PXR.2 抗体
PXR1 抗体
SAR 抗体
SXR 抗体
xonr1 抗体
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