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Niemann-Pick Disease, Type C1 蛋白

(Niemann-Pick Disease, Type C1 (NPC1))
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
NPC1 Protein (AA 151-250) (GST tag) NPC1 Protein (AA 151-250) (GST tag) NPC1 Protein (AA 151-250) (GST tag) (ABIN1312849)

NPC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

NPC1 Protein (His tag,DYKDDDDK Tag) NPC1 Protein (His tag,DYKDDDDK Tag) NPC1 Protein (His tag,DYKDDDDK Tag) (ABIN7317151)

NPC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.

NPC1 Protein (AA 372-620) (His tag) NPC1 Protein (AA 372-620) (His tag) NPC1 Protein (AA 372-620) (His tag) (ABIN3094184)

Crystallography grade NPC1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS

Niemann-Pick Disease, Type C1 蛋白 by Grade

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Niemann-Pick Disease, Type C1 蛋白 by Origin

Find Niemann-Pick Disease, Type C1 蛋白 for a variety of species such as anti-Human Niemann-Pick Disease, Type C1, anti-Mouse Niemann-Pick Disease, Type C1, anti-Rat Niemann-Pick Disease, Type C1. The species listed below are among those available. Click on a link to go to the corresponding products.

Niemann-Pick Disease, Type C1 蛋白 by Source

Here you will find Niemann-Pick Disease, Type C1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Niemann-Pick Disease, Type C1 蛋白 by 蛋白类型

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Niemann-Pick Disease, Type C1 蛋白 by 应用范围

Find Niemann-Pick Disease, Type C1 蛋白 validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Niemann-Pick Disease, Type C1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312849
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7317151
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3094184
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3131610
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094185
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094183
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131611
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131609
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3109756
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131608
Quantity 1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750647
Quantity 5 applications
Datasheet Datasheet

Aliases for Niemann-Pick Disease, Type C1 蛋白

NPC intracellular cholesterol transporter 1 (NPC1) 蛋白
NPC1 like intracellular cholesterol transporter 1 (Npc1l1) 蛋白
NPC intracellular cholesterol transporter 1 (Npc1) 蛋白
Niemann-Pick disease, type C1 (npc1) 蛋白
Niemann-Pick C1 protein (LOC579887) 蛋白
9130221N23Rik 蛋白
A430089E03Rik 蛋白
C85354 蛋白
Cdig2 蛋白
D18Ertd139e 蛋白
D18Ertd723e 蛋白
Gm243 蛋白
im:7149020 蛋白
lcsd 蛋白
nmf164 蛋白
NPC 蛋白
spm 蛋白
wu:fb53a12 蛋白
wu:fc29a12 蛋白
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