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NOTCH2 蛋白

(Notch 2 (NOTCH2))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
NOTCH2 Protein (His-Avi Tag,Biotin) NOTCH2 Protein (His-Avi Tag,Biotin) NOTCH2 Protein (His-Avi Tag,Biotin) (ABIN7275365)

NOTCH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

NOTCH2 Protein (AA 26-530) (Fc Tag) NOTCH2 Protein (AA 26-530) (Fc Tag) NOTCH2 Protein (AA 26-530) (Fc Tag) (ABIN7013569)

NOTCH2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

NOTCH2 Protein (AA 27-136) (GST tag) NOTCH2 Protein (AA 27-136) (GST tag) NOTCH2 Protein (AA 27-136) (GST tag) (ABIN1312811)

NOTCH2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

NOTCH2 蛋白 by Grade

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NOTCH2 蛋白 by Origin

Find NOTCH2 蛋白 for a variety of species such as anti-Human NOTCH2, anti-Mouse NOTCH2. The species listed below are among those available. Click on a link to go to the corresponding products.

NOTCH2 蛋白 by Source

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NOTCH2 蛋白 by 蛋白类型

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NOTCH2 蛋白 by 应用范围

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NOTCH2 蛋白 by 生物活性

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Popular NOTCH2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275365
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7013569
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312811
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7319906
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
  • (1)
Cat. No. ABIN1344244
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094222
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131583
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3114343
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3114342
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131582
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131581
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409635
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423015
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NOTCH2 蛋白

Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).

Aliases for NOTCH2 蛋白

neurogenic locus notch homolog protein 2 (LOC581186) 蛋白
notch 2 (NOTCH2) 蛋白
notch 3 (notch3) 蛋白
notch 2 (Notch2) 蛋白
notch 2 (notch2) 蛋白
AGS2 蛋白
AI853703 蛋白
HJCYS 蛋白
hN2 蛋白
N2 蛋白
notch6 蛋白
sb:cb884 蛋白
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