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TRAF2 抗体

(TNF Receptor-Associated Factor 2 (TRAF2))
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008].
TRAF2 抗体  (AA 1-300) TRAF2 抗体  (AA 1-300) TRAF2 抗体 (AA 1-300) (ABIN3021165)

TRAF2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

TRAF2 抗体  (AA 238-491) TRAF2 抗体  (AA 238-491) TRAF2 抗体 (AA 238-491) (ABIN7443455)

TRAF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

TRAF2 抗体  (C-Term) TRAF2 抗体  (C-Term) TRAF2 抗体 (C-Term) (ABIN190911)

Verified TRAF2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

TRAF2 抗体 by Grade

Find TRAF2 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TRAF2 抗体 by 适用

Find TRAF2 抗体 for a variety of species such as anti-Human TRAF2, anti-Mouse TRAF2, anti-Rat TRAF2. The species listed below are among those available. Click on a link to go to the corresponding products.

TRAF2 抗体 by 应用范围

Find TRAF2 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TRAF2 抗体 by 抗体来源

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TRAF2 抗体 by 抗原表位

Find TRAF2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TRAF2 抗体 by 克隆形成能力

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TRAF2 抗体 by 克隆

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TRAF2 抗体 by 标记

Find TRAF2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TRAF2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (1)
  • (8)
Cat. No. ABIN3021165
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7443455
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, FACS
Validations
  • (8)
Cat. No. ABIN190911
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (8)
Cat. No. ABIN5542488
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, FACS
Validations
  • (5)
Cat. No. ABIN7127853
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542489
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN673479
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7172232
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN521087
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257992
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN563253
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948588
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN521086
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265703
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN531962
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TRAF2 抗体

Wang, Cheng, Peng, Gao, Xi, Rousseaux, Khochbin, Wang, Mi: "Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1614-1626, (2018) (PubMed).

Akhtar, Singh, Ahmed: "MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 6, pp. 2219-28, (2017) (PubMed).

Döppler, Liou, Storz: "Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity." in: PLoS ONE, Vol. 8, Issue 1, pp. e53676, (2013) (PubMed).

Lei, Bai, Yang, Lai, Qiu, Yang, Lian: "Gsdma3 is a new factor needed for TNF-?-mediated apoptosis signal pathway in mouse skin keratinocytes." in: Histochemistry and cell biology, Vol. 138, Issue 3, pp. 385-96, (2012) (PubMed).

DAgostino, Giordano: "A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma." in: Oncotarget, Vol. 2, Issue 12, pp. 1055-74, (2012) (PubMed).

Shanmugam, Kusumanchi, Cheng, Crooks, Neelakantan, Matthews, Nakshatri, Sweeney: "A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species." in: The Prostate, Vol. 70, Issue 10, pp. 1074-86, (2010) (PubMed).

van Galen, Muris, Giroth, Vos, Ossenkoppele, Meijer, Oudejans: "Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas." in: Histopathology, Vol. 52, Issue 5, pp. 578-84, (2008) (PubMed).

Morrison, Bauer, Lupica, Tang, Schmidt, DiDonato, Lindner: "Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15349-56, (2007) (PubMed).

Merluzzi, DOrlando, Leonardi, Vitale, Pucillo: "TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation." in: Molecular immunology, Vol. 45, Issue 1, pp. 76-86, (2007) (PubMed).

Mainou, Everly, Raab-Traub: "Unique signaling properties of CTAR1 in LMP1-mediated transformation." in: Journal of virology, Vol. 81, Issue 18, pp. 9680-92, (2007) (PubMed).

Aliases for TRAF2 抗体

TNF-receptor-associated factor 2 (LOC661716) 抗体
conjugal transfer protein TraF (traF2) 抗体
TNF receptor associated factor 2 (TRAF2) 抗体
TNF receptor-associated factor 2 (Traf2) 抗体
Tnf receptor-associated factor 2 (Traf2) 抗体
AI325259 抗体
MGC:45012 抗体
TANK 抗体
TRAP 抗体
TRAP3 抗体
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