anti-马 Insulin 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

抗原
Insulin (INS) 抗体
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
适用
猫, 牛, 犬, 豚鼠, 马, 人, 猪, 兔, 大鼠, 绵羊
951
468
369
349
238
193
45
10
8
7
7
6
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
宿主
小鼠
785
196
49
9
4
2
1
克隆类型
单克隆
标记
This Insulin antibody is un-conjugated
52
41
36
21
20
20
20
15
15
15
13
13
13
13
13
13
13
10
9
9
7
7
7
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
461
356
275
269
258
237
180
118
106
67
66
31
25
23
21
8
7
5
4
4
4
3
2
2
2
1
1
1
1
1
1
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产品编号 ABIN114751
$ 308.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN114750 IHC (fro) IHC (p) Mouse IgG1 Log in to see K36aC10 0

General

抗原 Insulin (INS) 抗体
适用 猫, 牛, 犬, 豚鼠, 马, 人, 猪, 兔, 大鼠, 绵羊
(951), (468), (369), (349), (238), (193), (45), (10), (8), (7), (7), (6), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
宿主 小鼠
(785), (196), (49), (9), (4), (2), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This Insulin antibody is un-conjugated
(52), (41), (36), (21), (20), (20), (20), (15), (15), (15), (13), (13), (13), (13), (13), (13), (13), (10), (9), (9), (7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
应用范围 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(461), (356), (275), (269), (258), (237), (180), (118), (106), (67), (66), (31), (25), (23), (21), (8), (7), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2个引用可参考
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Insulin抗体详情

Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN114751) 图像
特异性 This antibody recognizes purified Insulin from the pancreas of Human, Bovine, Horse, Sheep as well as Proinsulin from Human. Cross reaction has been observed with insulin containing cells in fixed sections of pancreas from Human, Porcine, Dog, Rabbit, Bovine, Sheep, Rat, Guinea Pig and Cat.
Cellular Localization: Cytoplasmic.Cellular Localization
纯化方法 Supernatant
免疫原 Human insulin.
克隆位点 K36aC10
亚型 IgG1
Plasmids, Primers & others

Insulin目标详情

Insulin抗体详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN114751) 图像 回页首
抗原
别名 Insulin (INS Antibody 摘要)
背景 Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
基因ID 3630
NCBI登录号 NP_000198
UniProt P01308
途径 NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

使用细节

Insulin抗体详情 Insulin目标详情 贮存及处理 References for anti-Insulin antibody (ABIN114751) 图像 回页首
应用备注 Immunohistochemistry on Formalin/Paraffin Sections: Use a dilution of 1/25-1/50 in anABC method (30 minutes at room temperature). Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Insulin抗体详情 Insulin目标详情 使用细节 References for anti-Insulin antibody (ABIN114751) 图像 回页首
状态 Liquid
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN114751)

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 图像 回页首
背景

Madsen: "Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion." in: Diabetes, Vol. 36, Issue 10, pp. 1203-11, 1987

Keilacker, Dietz, Witt, Woltanski, Berling, Ziegler: "Kinetic properties of monoclonal insulin antibodies." in: Biomedica biochimica acta, Vol. 45, Issue 8, pp. 1093-102, 1986