anti-雪貂 Insulin 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

抗原
Insulin (INS) 抗体
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
适用
雪貂, 人, 猪, 大鼠
870
388
270
263
204
126
49
6
6
6
5
4
4
2
1
1
1
1
1
1
1
1
宿主

705
180
50
16
3
1
克隆类型
多克隆
标记
This Insulin antibody is un-conjugated
46
38
37
23
22
22
22
17
17
14
14
14
14
14
14
14
14
10
9
8
8
8
5
5
5
5
5
5
2
1
应用范围
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
500
370
234
227
189
181
146
123
66
64
32
25
15
11
7
6
5
4
4
3
2
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

产品编号 ABIN113504
$ 467.50
加上运输费 $45.00

General

抗原 Insulin (INS) 抗体
适用 雪貂, 人, 猪, 大鼠
(870), (388), (270), (263), (204), (126), (49), (6), (6), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
宿主
(705), (180), (50), (16), (3), (1)
克隆类型
多克隆
标记 This Insulin antibody is un-conjugated
(46), (38), (37), (23), (22), (22), (22), (17), (17), (14), (14), (14), (14), (14), (14), (14), (14), (10), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (2), (1)
应用范围 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(500), (370), (234), (227), (189), (181), (146), (123), (66), (64), (32), (25), (15), (11), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 找到1个引用
Supplier Log in to see

Insulin抗体详情

Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN113504) 图像
特异性 The antibody detects Insulin which is produced by the B-cells of the pancreatic islets. Antibody BP5053 can be used for the diagnosis of pancreatic B-cell tumors. Antigen localization: cytoplasm, extracellular.
纯化方法 Serum
免疫原 Porcine insulin

Insulin目标详情

Insulin抗体详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN113504) 图像 回页首
抗原
别名 Insulin (INS Antibody 摘要)
背景 Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
基因ID 3630
NCBI登录号 NP_000198
UniProt P01308
途径 NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

使用细节

Insulin抗体详情 Insulin目标详情 贮存及处理 References for anti-Insulin antibody (ABIN113504) 图像 回页首
应用备注 ELISA. Immunohistochemistry on frozen and paraffin sections: proteolytic treatment is notrequired, optimal results have been obtained by using the autoclave or microwave retrievalmethod (with citrate buffer). For immunohistochemistry dilute 1: 50 - 1: 100 (with PBS or TBS immediately before use),based on the indirect method, with a normal ABC method the dilution can be up to 5xhigher when using the microwave retrieval method. Recommended positive control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Insulin抗体详情 Insulin目标详情 使用细节 References for anti-Insulin antibody (ABIN113504) 图像 回页首
状态 Liquid
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN113504)

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 图像 回页首
背景

Luts, Sundler: "Peptide-containing nerve fibers in the respiratory tract of the ferret." in: Cell and tissue research, Vol. 258, Issue 2, pp. 259-67, 1990