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抗Human NPY1R 抗体:
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Bat Polyclonal NPY1R Primary Antibody for IHC (p) - ABIN270506
Matyal, Mahmood, Robich, Glazer, Khabbaz, Hess, Bianchi, Hagberg, Hu, Sellke: Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue. in European journal of pharmacology 2011
Human Monoclonal NPY1R Primary Antibody for ELISA, WB - ABIN562042
Igura, Haider, Ahmed, Sheriff, Ashraf: Neuropeptide y and neuropeptide y y5 receptor interaction restores impaired growth potential of aging bone marrow stromal cells. in Rejuvenation research 2011
the current review aims to compile, evaluate and summarise current knowledge on PYY, with particular emphasis on obesity and diabetes treatment, and the importance of specific Y receptor interactions for this.
crystal structures of the human Y1R bound to the two selective antagonists UR-MK299 and BMS-193885 at 2.7 and 3.0 A resolution, respectively
NPY1R plays an inhibitory role in tumor growth and may be a promising therapeutic target for Hepatocellular carcinoma
expressed in to B and T lymphocytes and mast cells in infantile hemangiomas
MAPK activation by NPY Y1 receptors is an internalization-independent pathway and that this receptor can transactivate the IGFR receptor.
Report design of argininamide-type NPY1R antagonists.
NPY and its Y receptor are possible mediators of both vasoconstriction and pulmonary vascular remodelling in pulmonary hypertension
Y1R expression in visceral adipose tissue might be an indicator of increased risk of metabolic syndrome.
The influence of beta-arrestin adaptors and endocytosis mechanisms on plasma membrane diffusion and particle brightness of GFP-tagged neuropeptide Y (NPY) receptors, was investigated.
Npy1 receptor transgene overexpression is associated with modest anxiolytic-like effect on mice in the open field and elevated plus maze tests.
For the first time we report a significant association between nicotine dependence and DRD5, NPY1R MAP3K4 single nucleotide polymorphism.
neuropeptide Y1 and Y2 receptors were expressed in 33 percent of testicular tumors and Y1 on intratumoral blood vessels in 50 percent of testicular tumors
The increased expression of NPY Y1 receptor may be related to local blood flow reduction and structural changes of pelvic supporting tissue in patients with pelvic organ prolapse.
A C-terminal tyrosine-based motif is critical for the constitutive internalization of Y(1) receptors lacking the last 32 C-terminal amino acids.
results suggest that the receptor-ligand interactions have changed during evolution after Y1 and Y2 arose from a common ancestral receptor
NPY1R and NPY5R have roles in nutrient-specific food intake in Europeans
Data suggest that neuropeptide Y modulates steroid production through Y1 receptors in human adrenal H295R cells.
the NPY Y(1) receptor induces the expression of CRE containing target genes through the CaM kinase-CREB pathway
Peptide YY and neuropeptide Y exert their effects through the NPY1 receptors in human colon mucosa.
human NPY Y1 and NPY Y2 receptors were detected in cerebral, meningeal, and coronary arteries using reverse transcriptase-polymerase chain reaction (RT-PCR); in addition, the trigeminal and superior cervical ganglia were positive for both receptors
Lower mRNA levels of neuropeptide Y receptor 1 (NPY1R) and NPY5R but not NPY or NPY2R in the central nucleus of the amygdala predicted elevated anxious temperament.
Results suggest that rabbit and human Y1, Y2 and Y5 receptor subtypes are well conserved, whereas Y4 receptors are less well conserved.
Neuropeptide Y (NPY\; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992
neuropeptide Y receptor type 1
, Neuropepetide Y1 Receptor
, neuropeptide Y1 receptor
, neuropeptide Y Y1 receptor
, G-protein coupled receptor
, neuropeptide Y receptor Y1
, Y1 neuropeptide Y receptor
, Neuropeptide Y receptor type 1
, gastric Y1 receptor
, neuropeptide Y receptor type 1-like
, NPY-1 receptor
, neuropeptide Y receptor subtype
, neuropeptide Y receptor Y1, NPY/PYY receptor Y1