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ABCC8 抗体

(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008].
ABCC8 抗体  (AA 679-929) ABCC8 抗体  (AA 679-929) ABCC8 抗体 (AA 679-929) (ABIN7441085)

ABCC8 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

ABCC8 抗体  (AA 1548-1582) (Atto 488) ABCC8 抗体  (AA 1548-1582) (Atto 488) ABCC8 抗体 (AA 1548-1582) (Atto 488) (ABIN2482986)

ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 488

ABCC8 抗体  (AA 1548-1582) (Atto 390) ABCC8 抗体  (AA 1548-1582) (Atto 390) ABCC8 抗体 (AA 1548-1582) (Atto 390) (ABIN2482985)

ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 390

ABCC8 抗体 by Grade

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Find ABCC8 抗体 for a variety of species such as anti-Human ABCC8, anti-Rat ABCC8, anti-Mouse ABCC8. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find ABCC8 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ABCC8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN7441085
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482986
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482985
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN1027723
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482997
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482996
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482993
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482995
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2483000
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482994
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482999
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN2482988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7144904
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7243895
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN520627
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ABCC8 抗体

Gerzanich, Stokum, Ivanova, Woo, Tsymbalyuk, Sharma, Akkentli, Imran, Aarabi, Sahuquillo, Simard: "Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion." in: Journal of neurotrauma, Vol. 36, Issue 7, pp. 1060-1079, (2019) (PubMed).

Luu, Bjork, Salo, Entenmann, Jurgenson, Fisher, Klein: "Modulation of SUR1 KATP Channel Subunit Activity in the Peripheral Nervous System Reduces Mechanical Hyperalgesia after Nerve Injury in Mice." in: International journal of molecular sciences, Vol. 20, Issue 9, (2019) (PubMed).

Vázquez-Sánchez, Hinojosa, Parraguirre-Martínez, González, Morales, Montalvo, Vera, Hernández-Gallegos, Camacho: "Expression of KATP channels in human cervical cancer: Potential tools for diagnosis and therapy." in: Oncology letters, Vol. 15, Issue 5, pp. 6302-6308, (2018) (PubMed).

Němcová-Fürstová, Kopperová, Balušíková, Ehrlichová, Brynychová, Václavíková, Daniel, Souček, Kovář: "Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters." in: Toxicology and applied pharmacology, Vol. 310, pp. 215-228, (2016) (PubMed).

Harel, Cohen, Hussain, Flanagan, Schlade-Bartusiak, Patel, Courtade, Li, Van Karnebeek, Kurata, Ellard, Chanoine, Gibson: "Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 28, Issue 3-4, pp. 345-51, (2015) (PubMed).

Bruin, Erener, Vela, Hu, Johnson, Kurata, Lynn, Piret, Asadi, Rezania, Kieffer: "Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells." in: Stem cell research, Vol. 12, Issue 1, pp. 194-208, (2014) (PubMed).

Karnik, Ludlow, Abuarab, Smith, Hardy, Elliott, Sivaprasadarao: "Endocytosis of HERG is clathrin-independent and involves arf6." in: PLoS ONE, Vol. 8, Issue 12, pp. e85630, (2014) (PubMed).

Li, Huang, Zhang, Kim, Yang, Kurata: "Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channels." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 23038-49, (2013) (PubMed).

Park, Ryu, Yu, Han, Ji, Oh, Sohn, Lim, Jeon, Lee, Lee, Lee, Berggren, Jeon, Ho: "Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic ?-cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12673-8, (2013) (PubMed).

de Wet, Rees, Shimomura, Aittoniemi, Patch, Flanagan, Ellard, Hattersley, Sansom, Ashcroft: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, (2007) (PubMed).

Aliases for ABCC8 抗体

ATP binding cassette subfamily C member 8 (ABCC8) 抗体
ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8) 抗体
ATP binding cassette subfamily C member 8 (Abcc8) 抗体
ABC36 抗体
D930031B21Rik 抗体
HHF1 抗体
HI 抗体
HRINS 抗体
MRP8 抗体
PHHI 抗体
SUR 抗体
Sur 抗体
SUR1 抗体
Sur1 抗体
SUR1delta2 抗体
TNDM2 抗体
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