anti-人 Proteasome (Prosome, Macropain) Subunit, alpha Type, 7 抗体 for Enzyme Immunoassay

Recommended Proteasome (Prosome, Macropain) Subunit, alpha Type, 7 Antibody (supplied by: Log in to see )

抗原
Proteasome (Prosome, Macropain) Subunit, alpha Type, 7 (PSMA7) 抗体
  • C6
  • HSPC
  • RC6-1
  • XAPC7
  • C6-I
  • DDBDRAFT_0185059
  • DDBDRAFT_0217080
  • DDB_0185059
  • DDB_0217080
  • hspc
  • rc6-1
  • xapc7
  • psma7
  • proteasome subunit alpha 7
  • proteasome (prosome, macropain) subunit, alpha type 7
  • 20S proteasome subunit alpha-7
  • proteasome subunit alpha 7 S homeolog
  • PSMA7
  • Psma7
  • psmA7
  • psma7
  • psma7.S
抗原表位
Middle Region
12
8
7
7
4
3
2
2
2
1
1
适用
人, 小鼠
97
40
25
1
宿主

81
16
克隆类型
多克隆
标记
非结合性
7
7
7
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
79
42
40
16
13
10
10
7
3
1
选项
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产品编号 ABIN453792
$ 484.00
加上运输费 $45.00

General

抗原 Proteasome (Prosome, Macropain) Subunit, alpha Type, 7 (PSMA7) 抗体
抗原表位 Middle Region
(12), (8), (7), (7), (4), (3), (2), (2), (2), (1), (1)
适用 人, 小鼠
(97), (40), (25), (1)
宿主
(81), (16)
克隆类型
多克隆
标记 非结合性
(7), (7), (7), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Enzyme Immunoassay (EIA), Western Blotting (WB)
(79), (42), (40), (16), (13), (10), (10), (7), (3), (1)
Pubmed 2个引用可参考
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产品细节

目标详细情况 使用细节 贮存及处理 引用 图像
特异性 This antibody reacts to PSMA7.
纯化方法 Affinity chromatography on Protein A
免疫原 KLH conjugated synthetic peptide selected from the Center region of human PSMA7

目标详细情况

产品细节 使用细节 贮存及处理 引用 图像 回页首
抗原
别名 PSMA7 (PSMA7 Antibody 摘要)
背景 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA7 is a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension.Synonyms: HSPC, Proteasome subunit RC6-1, Proteasome subunit XAPC7, Proteasome subunit alpha type-7
基因ID 5688
NCBI登录号 NP_002783
UniProt O14818
途径 Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

使用细节

产品细节 目标详细情况 贮存及处理 引用 图像 回页首
应用备注 ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

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状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

引用

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背景

Seeger, Ferrell, Frank, Dubiel: "HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8145-8, 1997

Huang, Kwong, Sun, Liang: "Proteasome complex as a potential cellular target of hepatitis B virus X protein." in: Journal of virology, Vol. 70, Issue 8, pp. 5582-91, 1996

图像

产品细节 目标详细情况 使用细节 贮存及处理 引用 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 7 (PSMA7) (Middle Region) antibody (ABIN453792) Western blot analysis of PSMA7 Antibody (Center) in mouse spleen tissue lysates (35ug...