anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) 抗体

6 Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) 抗体 from 2 manufacturers are available on www.antibodies-online.cn.

产品数据
  • 5
类型
  • 6
    一抗
抗原
  • 6
适用
  • 5
  • 1
应用范围
  • 5
  • 5
  • 1
  • 1
  • 1
抗体来源
  • 6
克隆形成能力
  • 6
抗原表位
  • 2
  • 1
  • 1
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抗体亚型
  • 6
Format
  • 6
6 产品
适用
应用范围 DB, ELISA
订购详情 分类号码 ABIN3030641
$452.38
加上运输费 $45.00
2至3个工作日
适用
应用范围 ELISA, WB
订购详情 分类号码 ABIN3030638
$452.38
加上运输费 $45.00
2至3个工作日
适用
应用范围 ELISA, WB
订购详情 分类号码 ABIN3028606
$452.38
加上运输费 $45.00
2至3个工作日
适用
应用范围 ELISA, WB
订购详情 分类号码 ABIN3030640
$452.38
加上运输费 $45.00
2至3个工作日
适用小鼠
应用范围 ELISA, WB
订购详情 分类号码 ABIN3030639
$452.38
加上运输费 $45.00
2至3个工作日
适用
应用范围 FACS, IF, IHC, WB
订购详情 分类号码 ABIN2797433
ISO
$467.50
400 μL
加上运输费 $45.00
6至8个工作日
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Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) 抗原简介

蛋白简介

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene\; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

Alternative names and synonyms associated with Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)

  • cyclin-dependent kinase inhibitor 2A (Cdkn2a) 抗体
  • cyclin-dependent kinase inhibitor 2A (LOC100731972) 抗体
  • cyclin-dependent kinase inhibitor 2A (LOC100340625) 抗体
  • cyclin dependent kinase inhibitor 2A (CDKN2A) 抗体
  • ARF 抗体
  • ARF-INK4a 抗体
  • CDK4I 抗体
  • CDKN2 抗体
  • CMM2 抗体
  • INK4 抗体
  • INK4A 抗体
  • INK4a-ARF 抗体
  • Ink4a/Arf 抗体
  • MLM 抗体
  • MTS-1 抗体
  • MTS1 抗体
  • P14 抗体
  • P14ARF 抗体
  • P16 抗体
  • p16(INK4a) 抗体
  • P16-INK4A 抗体
  • p16Cdkn2a 抗体
  • P16INK4 抗体
  • p16INK4a 抗体
  • P19 抗体
  • p19 抗体
  • P19ARF 抗体
  • Pctr1 抗体
  • TP16 抗体

Protein level used designations for CDKN2A

CDK4I , Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) , cell cycle inhibitor , cell cycle regulator , cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2a p16Ink4a , cyclin-dependent kinase inhibitor 2a p19Arf , p16-INK4 , p16-INK4a , CDK4 inhibitor p16-INK4 , cell cycle negative regulator beta , cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , multiple tumor suppressor 1 , cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4) , cyclin-dependent kinase inhibitor 2A, isoforms 1/2 , cyclin-dependent kinase inhibitor protein , mitochondrial smARF

GENE ID SPECIES
25163 Rattus norvegicus
100731972 Cavia porcellus
100340625 Oryctolagus cuniculus
1029 Homo sapiens
12578 Mus musculus
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