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PHGDH 抗体

(phosphoglycerate Dehydrogenase (PHGDH))
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011].
PHGDH 抗体  (AA 1-533) PHGDH 抗体  (AA 1-533) PHGDH 抗体 (AA 1-533) (ABIN565240)

PHGDH 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 4A3-1D6 unconjugated

PHGDH 抗体  (N-Term) PHGDH 抗体  (N-Term) PHGDH 抗体 (N-Term) (ABIN2855237)

KO Validated PHGDH 适用: 人 WB, IHC (p), IF, IP, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

PHGDH 抗体  (AA 264-533) PHGDH 抗体  (AA 264-533) PHGDH 抗体 (AA 264-533) (ABIN6145554)

PHGDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

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Find PHGDH 抗体 for a variety of species such as anti-Human PHGDH, anti-Mouse PHGDH, anti-Rat PHGDH. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular PHGDH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF, IP
Validations
  • (1)
  • (10)
Cat. No. ABIN565240
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, IP, IHC (fro), ICC
Validations
  • (6)
Cat. No. ABIN2855237
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN6145554
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (7)
Cat. No. ABIN3032221
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7149438
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3032220
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN949181
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN950075
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264177
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN389483
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN650767
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5650140
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p), IF, IP
Validations
  • (2)
Cat. No. ABIN626098
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (3)
Cat. No. ABIN2785892
Quantity 100 μL
Datasheet Datasheet
Reactivity Hamster, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6739000
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PHGDH 抗体

Ishida, Zhang, Bianchetti, Shu, Nguyen, Kleiner, Sanchez-Quintero, Quinzii, Westhoff, Karpel-Massler, Prabhu, Allen, Siegelin: "Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 21, pp. 5392-5406, (2018) (PubMed).

Liu, Liu, Yu, Lin, Chu, Deng, Yan, Li, Yao: "Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5093-5103, (2017) (PubMed).

Samanta, Park, Andrabi, Shelton, Gilkes, Semenza: "PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis." in: Cancer research, Vol. 76, Issue 15, pp. 4430-42, (2016) (PubMed).

Mattaini, Brignole, Kini, Davidson, Fiske, Drennan, Vander Heiden: "An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation." in: Cancer & metabolism, Vol. 3, pp. 5, (2015) (PubMed).

Markkanen, Fischer, Ledentcova, Kessler, Dianov: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).

DeNicola, Chen, Mullarky, Sudderth, Hu, Wu, Tang, Xie, Asara, Huffman, Wistuba, Minna, DeBerardinis, Cantley: "NRF2 regulates serine biosynthesis in non-small cell lung cancer." in: Nature genetics, Vol. 47, Issue 12, pp. 1475-81, (2015) (PubMed).

Maddocks, Berkers, Mason, Zheng, Blyth, Gottlieb, Vousden: "Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells." in: Nature, Vol. 493, Issue 7433, pp. 542-6, (2013) (PubMed).

Nilsson, Forshell, Rimpi, Kreutzer, Pretsch, Bornkamm, Nilsson: "Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis." in: PLoS genetics, Vol. 8, Issue 3, pp. e1002573, (2012) (PubMed).

Possemato, Marks, Shaul, Pacold, Kim, Birsoy, Sethumadhavan, Woo, Jang, Jha, Chen, Barrett, Stransky, Tsun, Cowley, Barretina, Kalaany, Hsu, Ottina, Chan, Yuan, Garraway, Root, Mino-Kenudson et al.: "Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. ..." in: Nature, Vol. 476, Issue 7360, pp. 346-50, (2011) (PubMed).

Pollari, Käkönen, Edgren, Wolf, Kohonen, Sara, Guise, Nees, Kallioniemi: "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis." in: Breast cancer research and treatment, Vol. 125, Issue 2, pp. 421-30, (2010) (PubMed).

Aliases for PHGDH 抗体

phosphoglycerate dehydrogenase (phgdh) 抗体
D-3-phosphoglycerate dehydrogenase (EDA9) 抗体
D-3-phosphoglycerate dehydrogenase (serA) 抗体
D-3-phosphoglycerate dehydrogenase (Sthe_2284) 抗体
D-3-phosphoglycerate dehydrogenase (Dacet_1260) 抗体
D-3-phosphoglycerate dehydrogenase (Mrub_0173) 抗体
phosphoglycerate dehydrogenase (MMAH_RS07650) 抗体
D-3-phosphoglycerate dehydrogenase (Arnit_0487) 抗体
D-3-phosphoglycerate dehydrogenase (Ndas_0174) 抗体
D-3-phosphoglycerate dehydrogenase (Mesil_2386) 抗体
D-3-phosphoglycerate dehydrogenase (Slip_0010) 抗体
D-3-phosphoglycerate dehydrogenase (Trad_0302) 抗体
D-3-phosphoglycerate dehydrogenase (Acear_0027) 抗体
D-3-phosphoglycerate dehydrogenase (Mahau_0665) 抗体
phosphoglycerate dehydrogenase (MZHIL_RS05165) 抗体
D-3-phosphoglycerate dehydrogenase (Mesop_1331) 抗体
D-3-phosphoglycerate dehydrogenase (Thein_0855) 抗体
3-phosphoglycerate dehydrogenase (Phgdh) 抗体
phosphoglycerate dehydrogenase (PHGDH) 抗体
phosphoglycerate dehydrogenase (Phgdh) 抗体
3-PGDH 抗体
3PGDH 抗体
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