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LGMN 抗体

(Legumain (LGMN))
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008].
LGMN 抗体  (AA 18-433) LGMN 抗体  (AA 18-433) LGMN 抗体 (AA 18-433) (ABIN7435007)

LGMN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

LGMN 抗体  (AA 18-435) LGMN 抗体  (AA 18-435) LGMN 抗体 (AA 18-435) (ABIN7440881)

LGMN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

LGMN 抗体  (AA 201-300) LGMN 抗体  (AA 201-300) LGMN 抗体 (AA 201-300) (ABIN750958)

LGMN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

LGMN 抗体 by 适用

Find LGMN 抗体 for a variety of species such as anti-Human LGMN, anti-Mouse LGMN, anti-Rat LGMN. The species listed below are among those available. Click on a link to go to the corresponding products.

LGMN 抗体 by 应用范围

Find LGMN 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LGMN 抗体 by 抗体来源

Find LGMN 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

LGMN 抗体 by 抗原表位

Find LGMN 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LGMN 抗体 by 克隆形成能力

Find available monoclonal or polyclonal LGMN 抗体. Click on a link to go to the corresponding products.

LGMN 抗体 by 克隆

Find LGMN 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

LGMN 抗体 by 标记

Find LGMN 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LGMN 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7435007
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7440881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN750958
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6143172
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN519319
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN519317
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (3)
Cat. No. ABIN7255373
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN519318
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7157971
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN562455
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1804571
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN1881495
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IP
Validations
  • (1)
Cat. No. ABIN562456
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1909740
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our LGMN 抗体

Garcia-Cattaneo, Gobert, Müller, Toscano, Flores, Lescure, Del Nery, Benaroch: "Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 23, pp. 9053-8, (2012) (PubMed).

Liu, Bajjuri, Liu, Sinha: "Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug." in: Molecular pharmaceutics, Vol. 9, Issue 1, pp. 168-75, (2012) (PubMed).

Clerin, Shih, Deng, Hebert, Resmini, Shields, Feldman, Winkler, Albert, Maganti, Wong, Paulsen, Keith, Vlasuk, Pittman: "Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis." in: Atherosclerosis, Vol. 201, Issue 1, pp. 53-66, (2009) (PubMed).

Liu, Jang, Liu, Cheng, Peng, Yepes, Li, Matthews, Watts, Asano, Hara-Nishimura, Luo, Ye: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." in: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).

Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, (2005) (PubMed).

Aliases for LGMN 抗体

legumain (LGMN) 抗体
legumain (Lgmn) 抗体
legumain L homeolog (lgmn.L) 抗体
legumain (lgmn) 抗体
delta vacuolar processing enzyme (DELTA-VPE) 抗体
legumain (MBOO_RS07785) 抗体
Legumain (Odosp_3582) 抗体
legumain (LOC569153) 抗体
AEP 抗体
AI746452 抗体
AU022324 抗体
cb173 抗体
cb460 抗体
DELTA VACUOLAR PROCESSING ENZYME 抗体
delta vacuolar processing enzyme 抗体
DELTAVPE 抗体
lgmn 抗体
LGMN1 抗体
MGC64351 抗体
MGC88980 抗体
PRSC1 抗体
Prsc1 抗体
sb:cb173 抗体
wu:fa98g05 抗体
wu:fj92g08 抗体
zgc:76953 抗体
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