anti-小鼠 Paxillin 抗体 for Western Blotting

Recommended Paxillin Antibody (supplied by: Log in to see )

抗原
Paxillin (PXN) 抗体
  • AW108311
  • AW123232
  • Pax
  • CG18061
  • CG18576
  • CG31794
  • CT40481
  • CT42454
  • DPaxillin
  • DPxn
  • DPxn37
  • Dmel\\CG31794
  • Dpax
  • DpaxA
  • PDLP
  • dPax
  • pax
  • wu:fw71f12
  • PXN
  • LOC100220858
  • paxillin
  • Paxillin
  • paxillin S homeolog
  • paxillin a
  • PXN
  • Pxn
  • Pax
  • pxn.S
  • pxna
  • LOC696336
  • pxn
抗原表位
AA 456-472, C-Term
67
52
28
20
16
15
15
13
13
10
8
7
6
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
392
208
197
32
12
11
11
9
5
5
5
4
1
1
1
1
1
宿主

355
45
2
克隆类型
多克隆
标记
This Paxillin antibody is un-conjugated
7
7
7
5
5
5
5
5
5
5
5
5
4
4
2
2
2
2
2
应用范围
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
318
110
86
64
54
48
28
23
8
5
3
2
2
2
1
1
1
选项
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产品编号 ABIN3044187
$ 280.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2318885 ABIN3043666 ICC WB Mouse IgG1 AA 305-559, C-Term Log in to see PXC-10 3
3.2318885 ABIN968067 IF IP IHC WB Mouse IgG1 AA 1-557 Log in to see 165-Paxillin 5
3.2318885 ABIN2706774 IP IHC WB Rabbit Center Log in to see Polyclonal 0
3.2318885 ABIN2706775 WB Rabbit pTyr118 Log in to see Polyclonal 0
3.2318885 ABIN447010 ICC IF IHC (p) IHC WB Rabbit N-Term Log in to see Polyclonal 1
3.2318885 ABIN968042 BI IP WB Mouse IgG1 AA 1-557 Log in to see 177-Paxillin 5
3.2318885 ABIN968043 BI IP IHC WB Mouse IgG1 AA 1-557 Log in to see 177-Paxillin 5
3.2318885 ABIN1531947 ELISA WB Rabbit IgG AA 15-64, pTyr31 Log in to see Polyclonal 0
3.2318885 ABIN1531946 ELISA WB Rabbit IgG AA 85-134, pTyr118 Log in to see Polyclonal 0
3.2318885 ABIN1532978 IHC ELISA WB Rabbit IgG AA 85-134 Log in to see Polyclonal 0
3.2318885 ABIN967711 IHC (f) IF IP WB Mouse IgG1 AA 1-557 Log in to see 349-Paxillin 5
3.2318885 ABIN967712 IHC (f) IF IP WB Mouse IgG1 AA 1-557 Log in to see 349-Paxillin 5
3.2318885 ABIN1532979 IHC ELISA WB Rabbit IgG AA 15-64 Log in to see Polyclonal 0
3.2318885 ABIN968066 IF IP IHC WB Mouse IgG1 AA 1-557 Log in to see 165-Paxillin 4
3.2318885 ABIN408463 WB Rabbit IgG pTyr118 Log in to see Polyclonal 0
3.2318885 ABIN1870552 WB Rabbit IgG pTyr31 Log in to see Polyclonal 0
3.2318885 ABIN1870550 IHC WB Rabbit IgG pTyr118 Log in to see Polyclonal 0
3.2318885 ABIN1874479 IHC IP WB Rabbit IgG Log in to see Polyclonal 0
3.2318885 ABIN3186343 ELISA IF IHC WB Rabbit IgG Thr507 Log in to see Polyclonal 0
3.2318885 ABIN3182119 ELISA IHC WB Rabbit IgG pTyr31 Log in to see Polyclonal 0

General

抗原 Paxillin (PXN) 抗体
抗原表位 AA 456-472, C-Term
(67), (52), (28), (20), (16), (15), (15), (13), (13), (10), (8), (7), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(392), (208), (197), (32), (12), (11), (11), (9), (5), (5), (5), (4), (1), (1), (1), (1), (1)
宿主
(355), (45), (2)
克隆类型
多克隆
标记 This Paxillin antibody is un-conjugated
(7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2)
应用范围 Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(318), (110), (86), (64), (54), (48), (28), (23), (8), (5), (3), (2), (2), (2), (1), (1), (1)
Pubmed 3个引用可参考
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Paxillin抗体详情

Paxillin目标详情 使用细节 贮存及处理 References for anti-Paxillin antibody (ABIN3044187) 图像
原理 Rabbit IgG polyclonal antibody for Paxillin(PXN) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
序列 HEKDGKAYCR KDYFDMF
交叉反应 (详细) No cross reactivity with other proteins.
产品特性 Rabbit IgG polyclonal antibody for Paxillin(PXN) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: paxillin
Protein Name: Paxillin
纯化方法 Immunogen affinity purified.
免疫原 A synthetic peptide corresponding to a sequence at the C-terminal of human Paxillin(456-472aa HEKDGKAYCRKDYFDMF), identical to the related mouse and rat sequences.
亚型 IgG

Paxillin目标详情

Paxillin抗体详情 使用细节 贮存及处理 References for anti-Paxillin antibody (ABIN3044187) 图像 回页首
抗原
别名 PXN (PXN Antibody 摘要)
背景 PXN(Paxillin) is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge. Salgia et al.(1995) mapped the paxillin gene to 12q24 using fluorescence in situ hybridization.The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions, it is presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein-protein interaction sites. The proteins that bind to paxillin are diverse and include protein tyrosine kinases, such as Src and FAK, structural proteins, such as vinculin and actopaxin, and regulators of actin organization, such as COOL/PIX and PKL/GIT. Paxillin is tyrosine-phosphorylated by FAK and Src upon integrin engagement or growth factor stimulation, creating binding sites for the adapter protein Crk.The paxillin protein contains 4 LIM domains, a proline-rich domain containing a consensus SH3-binding site, and 3 potential SH2-binding sites. On Northern blots, paxillin was expressed as a 3.7-kb mRNA in all tissues tested.

Synonyms: FLJ16691 antibody|FLJ23042 antibody|Paired box protein Pax 1 antibody|PAX 1 antibody|PAX1 antibody|PAXI_HUMAN antibody|Paxillin alpha antibody|Paxillin antibody|PXN antibody|PXN protein antibody
UniProt P49023
途径 MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling

使用细节

Paxillin抗体详情 Paxillin目标详情 贮存及处理 References for anti-Paxillin antibody (ABIN3044187) 图像 回页首
应用备注 WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

限制 仅限研究用

贮存及处理

Paxillin抗体详情 Paxillin目标详情 使用细节 References for anti-Paxillin antibody (ABIN3044187) 图像 回页首
状态 Lyophilized
溶解方式 Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
浓度 500 μg/mL
缓冲液 Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
储存液 Thimerosal (Merthiolate), Sodium azide
注意事项 This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
有效期 12 months

References for anti-Paxillin antibody (ABIN3044187)

Paxillin抗体详情 Paxillin目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, 2014

Zhong, Luo, Wang, Tang, Wu, Wang, Huang, Sun, Huang: "Effects of polydopamine functionalized titanium dioxide nanotubes on endothelial cell and smooth muscle cell." in: Colloids and surfaces. B, Biointerfaces, Vol. 116, pp. 553-60, 2014

图像

Paxillin抗体详情 Paxillin目标详情 使用细节 贮存及处理 References for anti-Paxillin antibody (ABIN3044187) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, Western blotting Lane 1: 293T Cell Lysate Lane 2: HELA Cell L...
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, IHC(F) IHC(F): Rat Kidney Tissue
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, IHC(P) IHC(P): Human Lung Cancer Tissue
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, ICC ICC: HELA Cell