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Human p38 ELISA Kit for Cell ELISA - ABIN1981835
Han, Lee, Bibbs, Ulevitch: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. in Science (New York, N.Y.) 1994
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Human p38 ELISA Kit for Sandwich ELISA - ABIN625229
Brenner, Rosenhagen, Brandt, Schmitt, Jung, Schemmer, Schmidt, Mieth, Bruckner, Lichtenstern, Martin, Weigand, Hofer: Cell death biomarkers as early predictors for hepatic dysfunction in patients after orthotopic liver transplantation. in Transplantation 2012
Overall, these results suggest that p53 (显示 TP53 ELISA试剂盒) is involved in improving insulin (显示 INS ELISA试剂盒) sensitivity of hepatic cells via inhibition of mitogen-activated protein kinases (MAPKs) and NF-kappaB (显示 NFKB1 ELISA试剂盒) pathways.
Data show that the combination of targeting RAD51 (显示 RAD51 ELISA试剂盒) and p38 (显示 CRK ELISA试剂盒) inhibits cell proliferation both in vitro and in vivo, which was further enhanced by targeting of PARP1 (显示 PARP1 ELISA试剂盒).
Fas-FasL is the preferred death pathway for both Th1 and Th17 and that inherently low Erk2 activity protected Th17 cells from TCR AICD.
provide the first report that p38 (显示 CRK ELISA试剂盒)-p38IP (显示 SUPT20H ELISA试剂盒) is required for the Snail (显示 SNAI1 ELISA试剂盒)-induced E-cadherin (显示 CDH1 ELISA试剂盒) down-regulation and cell invasion in HNSCC
GATA4 (显示 GATA4 ELISA试剂盒) is a regulator of osteoblastic differentiation via the p38 (显示 CRK ELISA试剂盒) signaling pathways.
CX3CL1 (显示 CX3CL1 ELISA试剂盒)/CX3CR1 (显示 CX3CR1 ELISA试剂盒) axis plays a key role in the development of ischemia-induced oligodendrocyte injury via p38MAPK (显示 MAPK14 ELISA试剂盒) signaling pathway.
Data suggest that in vitro-induction of CD8 (显示 CD8A ELISA试剂盒)+ Tregs depended in part on transforming growth factor beta 1 (TGF-beta1 (显示 TGFB1 ELISA试剂盒)) activation of p38 MAPK (显示 MAPK14 ELISA试剂盒) signaling, and that p38 MAPK (显示 MAPK14 ELISA试剂盒) could be a therapeutic target in ovarian cancer (OC) anti-tumor immunotherapy.
present study provides evidence that variations in GADD45B (显示 GADD45B ELISA试剂盒) rs2024144T, MAPK14 (显示 MAPK14 ELISA试剂盒) rs3804451A and GADD45A (显示 GADD45A ELISA试剂盒) rs581000C may predict platinum-based chemotherapy toxicity outcomes in patients with advanced non-small cell lung cancer
Gab1/SHP2 (显示 PTPN11 ELISA试剂盒)/p38MAPK (显示 MAPK14 ELISA试剂盒) signaling pathway and Ang-2 (显示 ANGPT2 ELISA试剂盒) have an essential role in regulating thrombin (显示 F2 ELISA试剂盒)-induced monocyte adhesion and vascular leakage
Studies suugest Wip1 (显示 PPM1D ELISA试剂盒) role in tumorigenesis through regulation of p53 (显示 TP53 ELISA试剂盒) and p38MAPK (显示 MAPK14 ELISA试剂盒) pathways.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.