anti-犬 ERK2 抗体 for Immunofluorescence

Recommended ERK2 Antibody (supplied by: Log in to see )

抗原
Mitogen-Activated Protein Kinase 1 (MAPK1) 抗体
  • ERK
  • ERK2
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • zERK2
  • MAPK1
  • Xp42
  • erk
  • erk2
  • ert1
  • mapk
  • mapk1b
  • mapk2
  • mpk1
  • prkm1
  • prkm2
  • mapk1
  • mapk1a
  • xp42
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 1
  • mitogen activated protein kinase 1
  • mitogen-activated protein kinase 1 L homeolog
  • mitogen-activated protein kinase 1 S homeolog
  • MAPK1
  • Mapk1
  • mapk1
  • mapk1.L
  • mapk1.S
  • PfMAP1
  • MPK1
  • PVX_084965
  • LOC9328617
  • Tsp_01601
抗原表位
AA 219-358
59
21
16
11
9
8
8
8
5
5
4
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
小鸡, 犬, Frog, 人, 小鼠, 大鼠
352
149
118
51
30
19
14
10
10
9
9
7
5
5
2
2
2
2
1
1
1
宿主
小鼠
168
168
16
8
3
克隆类型
单克隆
标记
This ERK2 antibody is un-conjugated
10
9
8
7
7
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
1
应用范围
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
329
161
95
82
82
60
53
27
23
10
5
3
3
2
2
1
1
1
1
1
1
1
1
选项
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产品编号 ABIN967748
产品在该地区无法提供。
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.713779 ABIN967747 IF IP IHC WB Mouse IgG2b AA 219-358 Log in to see 33-ERK2 5
11.713779 ABIN2452330 IF IP WB Mouse IgG2a Log in to see 7C9 0
11.713779 ABIN2452333 IF IP WB Mouse IgG1 Log in to see 7E7 0
1 ABIN1499289 IF IHC (p) IP WB Mouse IgG1 Log in to see 4C2 0
1 ABIN1499290 IF IP WB Mouse IgG1 Log in to see 7E7 0
1 ABIN1499288 IF WB Mouse IgG2a Log in to see 7C9 0
1 ABIN2452608 IF IP IHC WB Mouse IgG1 Log in to see 4C2 0
1 ABIN2742748 ChIP IF IHC (p) IP WB Mouse IgG2a Log in to see 6F8 0
1 ABIN2625131 IF IHC (p) PLA WB Rabbit IgG AA 310-360 Log in to see Polyclonal 0
1 ABIN1911863 IF IHC (p) Rabbit IgG AA 310-360 Log in to see Polyclonal 0

General

抗原 Mitogen-Activated Protein Kinase 1 (MAPK1) 抗体
抗原表位 AA 219-358
(59), (21), (16), (11), (9), (8), (8), (8), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 小鸡, 犬, Frog, 人, 小鼠, 大鼠
(352), (149), (118), (51), (30), (19), (14), (10), (10), (9), (9), (7), (5), (5), (2), (2), (2), (2), (1), (1), (1)
宿主 小鼠
(168), (168), (16), (8), (3)
克隆类型 (克隆位点)
单克隆   ( )
标记 This ERK2 antibody is un-conjugated
(10), (9), (8), (7), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
应用范围 Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(329), (161), (95), (82), (82), (60), (53), (27), (23), (10), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5个引用可参考
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ERK2抗体详情

ERK2目标详情 使用细节 贮存及处理 References for anti-ERK2 antibody (ABIN967748) 图像
交叉反应 人, 犬, 小鼠, 小鸡, Frog
产品特性 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Rat ERK2 aa. 219-358
克隆位点 33-ERK2
亚型 IgG2b

ERK2目标详情

ERK2抗体详情 使用细节 贮存及处理 References for anti-ERK2 antibody (ABIN967748) 图像 回页首
抗原
别名 ERK2 (MAPK1 Antibody 摘要)
背景 The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a wide variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. Structural analysis of ERK2 indicates that phosphorylation induces a conformational change that exposes the active site for substrate binding. Myriad proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK2 is the 42kDa member of the ERK family and is highly homologous to ERK1.
分子量 42 kDa
途径 MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

使用细节

ERK2抗体详情 ERK2目标详情 贮存及处理 References for anti-ERK2 antibody (ABIN967748) 图像 回页首
说明

Related Products: ABIN967389

限制 仅限研究用

贮存及处理

ERK2抗体详情 ERK2目标详情 使用细节 References for anti-ERK2 antibody (ABIN967748) 图像 回页首
状态 Liquid
浓度 250 μg/mL
缓冲液 Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store undiluted at -20°C.

References for anti-ERK2 antibody (ABIN967748)

ERK2抗体详情 ERK2目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Kim, Ju, Oh, Yoon, Song, Kim, Yoo, Bang, Kang, Chun: "ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status." in: The Journal of biological chemistry, Vol. 277, Issue 2, pp. 1332-9, 2002

Lehmann, Janda, Pierreux, Rytömaa, Schulze, McMahon, Hill, Beug, Downward: "Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells." in: Genes & development, Vol. 14, Issue 20, pp. 2610-22, 2000

Liu, Tsai, Aird: "Egr-1 gene is induced by the systemic administration of the vascular endothelial growth factor and the epidermal growth factor." in: Blood, Vol. 96, Issue 5, pp. 1772-81, 2000

Lund-Johansen, Davis, Bishop, de Waal Malefyt: "Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions." in: Cytometry, Vol. 39, Issue 4, pp. 250-9, 2000

Visconti, Gadina, Chiariello, Chen, Stancato, Gutkind, OShea: "Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity." in: Blood, Vol. 96, Issue 5, pp. 1844-52, 2000

图像

ERK2抗体详情 ERK2目标详情 使用细节 贮存及处理 References for anti-ERK2 antibody (ABIN967748) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967748) Western blot analysis of ERK2 on rat pituitary lysate. Lane 1: 1:5000, lane 2: 1:1000...
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967748) Immunofluorescence staining of MCF7 cells.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967748) ERK 2 (clone 33) staining on rat brain. Formalin fixed paraffin section with citrate ...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967748) anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (Image 4)