Use your antibodies-online credentials, if available.
抗Human PDIA3 抗体:
抗Mouse (Murine) PDIA3 抗体:
抗Rat (Rattus) PDIA3 抗体:
Human Polyclonal PDIA3 Primary Antibody for ICC, IF - ABIN4309513
Racapé, Duong Van Huyen, Danger, Giral, Bleicher, Foucher, Pallier, Pilet, Tafelmeyer, Ashton-Chess, Dugast, Pettré, Charreau, Soulillou, Brouard: The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response. in PLoS ONE 2011
Show all 4 Pubmed References
Cow (Bovine) Monoclonal PDIA3 Primary Antibody for ICC, IF - ABIN361814
Chen, Gharib, Huang, Thomas, Shedden, Taylor, Kardia, Misek, Giordano, Iannettoni, Orringer, Hanash, Beer: Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Show all 12 Pubmed References
Human Polyclonal PDIA3 Primary Antibody for ICC, IF - ABIN4309514
Kashyap, Harsha, Renuse, Pawar, Sahasrabuddhe, Kim, Marimuthu, Keerthikumar, Muthusamy, Kandasamy, Subbannayya, Prasad, Mahmood, Chaerkady, Meltzer, Kumar, Rustgi, Pandey: SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. in Cancer biology & therapy 2011
Show all 2 Pubmed References
Human Polyclonal PDIA3 Primary Antibody for WB - ABIN516210
Schulz, Leuschen, Fröhlich, Lorenz, Pfeiler, Gleissner, Kremmer, Kessler, Khandoga, Engelmann, Ley, Massberg, Arnold: Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation. in Blood 2010
Human Polyclonal PDIA3 Primary Antibody for ELISA, WB - ABIN249726
Koivunen, Horelli-Kuitunen, Helaakoski, Karvonen, Jaakkola, Palotie, Kivirikko: Structures of the human gene for the protein disulfide isomerase-related polypeptide ERp60 and a processed gene and assignment of these genes to 15q15 and 1q21. in Genomics 1997
Human Monoclonal PDIA3 Primary Antibody for ICC, IF - ABIN4309510
Dursun, Gezen-Ak: Vitamin D receptor is present on the neuronal plasma membrane and is co-localized with amyloid precursor protein, ADAM10 or Nicastrin. in PLoS ONE 2017
Study demonstrated that the expression of PDIA3 is frequently upregulated at the mRNA and protein levels in diffuse gliomas. Its high expression was significantly correlated with high Ki-67 (显示 MKI67 抗体), more TP53 (显示 TP53 抗体) mutations and poor survival outcome. These findings imply that high expression of PDIA3 plays an important role in diffuse glioma progression.
summarize available knowledge of ERp57's functions in subcellular compartments and the roles of dysregulated ERp57 in various diseases.
ERp57 is involved in sperm capacitation and spermatozoa-zona pellucida binding.
Thiol isomerase ERp57 is mobilized to the surface of activated platelets via a process that requires actin polymerization.
Findings suggested that miR (显示 MLXIP 抗体)-330-5p represents a potential tumor-suppressive miRNA and plays an important role in cutaneous malignant melanoma progression by suppressing TYR (显示 TYR 抗体) and PDIA3 expression.
Our study found increased expression of ERp57 in chronic hepatitis B -hepatocellular carcinoma (HBV-HCC (显示 FAM126A 抗体)) genesis. Such altered expression could be related to HBV infection and high ERp57 expression may lead to poor prognosis of HBV-HCC (显示 FAM126A 抗体) patients.
The interaction of different flavonoids with PDIA3 was investigated by quenching fluorescence analysis and the effects on protein activity were evaluated.
Upregulation of PDIA3 promotes ovarian cancer cell proliferation and migration.
Data show that knockdown of endoplasmic reticulum resident protein 57 (ERP57) expression resulted in increase in shikonin induced apoptosis, and suggest that ERP57 might be a therapeutic option for the treatment of acute myeloid leukemia (显示 BCL11A 抗体).
Amyotrophic lateral sclerosis-linked PDIA3 mutations disrupt motor neuron connectivity.
These results suggest that Tat (显示 TAT 抗体)-PDIA3 could be used to protect spinal cord neurons from ischemic damage, due to its modulatory action on the oxidative/anti-oxidative balance. Tat (显示 TAT 抗体)-PDIA3 could be applicable to protects neurons from the ischemic damage induced by thoracoabdominal aorta obstruction.
results demonstrate that the core circadian gene Clock regulates bone formation via transcriptional control of 1,2,5(OH)2D3 receptor PDIA3
These data indicate a synergistic crosstalk between 1alpha,25(OH)2D3 and BMP2 (显示 BMP2 抗体) toward osteogenesis and mineral deposition, involving both VDR (显示 CYP27B1 抗体) and Pdia3.
ERp57 deficiency causes neuromuscular defects
ERp57 levels are increased in the airway epithelium of asthmatic patients and in mice with allergic airways disease.
Data suggest that regulation of Pdia3 (protein disulfide isomerase associated 3 protein) expression by microRNA-330-5p is important in maintaining hair cycle through regulation of proliferation and migration capability of keratinocytes.
All the growth plate and bone abnormalities, however, become attenuated after the pubertal growth spurt (显示 BPIFA1 抗体), when protein synthesis is decelerated and, hence, ERp57 function is less essential.
a Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体)-driven functional role of ENO1 and PDIA3 in alveolar epithelial cell plasticity in lung injury and repair, is reported.
ERp57 regulates thrombosis via multiple targets.
These data suggest the 25D3 -MARRS receptor/PDIA3/ERp57 may contribute to the length of lifespan in mammals.
PDIA3 may play in the progression of heart failure.
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase\; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
58 kDa glucose-regulated protein
, 58 kDa microsomal protein
, ER protein 57
, ER protein 60
, disulfide isomerase ER-60
, endoplasmic reticulum P58
, endoplasmic reticulum resident protein 57
, endoplasmic reticulum resident protein 60
, glucose regulated protein, 58kDa
, phospholipase C-alpha
, protein disulfide isomerase-associated 3
, protein disulfide-isomerase A3
, glucose regulated protein 58
, endoplasmic reticulum protein
, glucose regulated protein, 58 kDa
, phospholipase C, alpha
, ER-60 protease
, oxidoreductase ERp57
, protein disulfide isomerase associated 3
, glucose regulated protein 58kD
, 1,25D3-MARRS protein
, 1,25D3-membrane-associated, rapid-response steroid-binding protein
, 25D3-MARRS protein
, glucose regulated thiol oxidoreductase protein
, glucose-regulated thiol oxidoreductase 58 kDa protein
, rapid-response steroid-binding protein
, glucose regulated protein
, protein disulfide isomerase family A member 3 S homeolog
, protein disulfide isomerase family A, member 3