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CTNNA1 抗体

(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
CTNNA1 抗体  (C-Term) CTNNA1 抗体  (C-Term) CTNNA1 抗体 (C-Term) (ABIN6260492)

CTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

CTNNA1 抗体  (AA 637-906) CTNNA1 抗体  (AA 637-906) CTNNA1 抗体 (AA 637-906) (ABIN6139202)

CTNNA1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

CTNNA1 抗体 CTNNA1 抗体 CTNNA1 抗体 (ABIN7261582)

CTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

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Popular CTNNA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
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Cat. No. ABIN6260492
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (8)
Cat. No. ABIN6139202
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7261582
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
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Cat. No. ABIN3043818
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
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Cat. No. ABIN185626
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (4)
Cat. No. ABIN5542501
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7440782
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
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Cat. No. ABIN7146972
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN514753
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7138670
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7234862
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IF
Validations
  • (2)
Cat. No. ABIN6939199
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN540503
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7266133
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
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Cat. No. ABIN390505
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our CTNNA1 抗体

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).

Bajpai, Feng, Krishnamurthy, Longmore, Wirtz: "Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells." in: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18252-9, (2009) (PubMed).

Yamada, Pokutta, Drees, Weis, Nelson: "Deconstructing the cadherin-catenin-actin complex." in: Cell, Vol. 123, Issue 5, pp. 889-901, (2005) (PubMed).

Drees, Pokutta, Yamada, Nelson, Weis: "Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly." in: Cell, Vol. 123, Issue 5, pp. 903-15, (2005) (PubMed).

Hwang, Yu, Ryu, Jeon, Yoo, Eom, Chun: "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12758-65, (2005) (PubMed).

Lynch, Grady, Suriano, Huntsman: "Gastric cancer: new genetic developments." in: Journal of surgical oncology, Vol. 90, Issue 3, pp. 114-33; discussion 133, (2005) (PubMed).

Lin, Wu, Li, Wu, Zheng: "Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma." in: World journal of gastroenterology, Vol. 10, Issue 22, pp. 3235-9, (2005) (PubMed).

Katafiasz, Nieman, Wheelock, Johnson: "Characterization of cadherin-24, a novel alternatively spliced type II cadherin." in: The Journal of biological chemistry, Vol. 278, Issue 30, pp. 27513-9, (2003) (PubMed).

Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

Giannini, Vivanco, Kypta: "alpha-catenin inhibits beta-catenin signaling by preventing formation of a beta-catenin*T-cell factor*DNA complex." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 21883-8, (2000) (PubMed).

Aliases for CTNNA1 抗体

catenin alpha 1 (CTNNA1) 抗体
catenin (cadherin associated protein), alpha 1 (Ctnna1) 抗体
catenin alpha 1 (Ctnna1) 抗体
alpha Catenin (alpha-Cat) 抗体
alpha Catenin (Dgri\alpha-Cat) 抗体
catenin alpha-1 (Tsp_10127) 抗体
catenin (cadherin-associated protein), alpha 1 (ctnna1) 抗体
catenin alpha 1 S homeolog (ctnna1.S) 抗体
2010010M04Rik 抗体
a-Cat 抗体
a-cat 抗体
AA517462 抗体
AI988031 抗体
alpha-CAT 抗体
alpha-cat 抗体
Alpha-Cat 抗体
alpha-catenin 抗体
alpha-ctn 抗体
alphaCAT 抗体
alphaCat 抗体
alphacat 抗体
CAP102 抗体
cap102 抗体
Catna1 抗体
catna1 抗体
CG17947 抗体
CT39986 抗体
ctnna 抗体
ctnna1 抗体
Dalpha-Cat 抗体
Dalpha-cat 抗体
DalphaC 抗体
Dalphacat 抗体
DgriGH19548 抗体
dgri_GLEANR_3829 抗体
Dmcatp 抗体
Dmel\\CG17947 抗体
GH19548 抗体
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