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Leucine-Rich, Glioma Inactivated 1 产品

(Leucine-Rich, Glioma Inactivated 1 (LGI1))

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This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008].

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Featured Leucine-Rich, Glioma Inactivated 1 Categories

Leucine-Rich, Glioma Inactivated 1 抗体

High quality antibodies with extensive validation data.

Leucine-Rich, Glioma Inactivated 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Leucine-Rich, Glioma Inactivated 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Leucine-Rich, Glioma Inactivated 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN720430
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741270
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741269
Quantity 100 μg
Datasheet Datasheet

Recommended Leucine-Rich, Glioma Inactivated 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6973524
Quantity 96 tests
Datasheet Datasheet

Recommended Leucine-Rich, Glioma Inactivated 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309348
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083026
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130053
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Leucine-Rich, Glioma Inactivated 1 Products

Fialka, Gruber, Hitt, Opitz, Brunner, Schliephake, Kramer: "CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma--a pilot study." in: Oral oncology, Vol. 44, Issue 10, pp. 941-8, (2008) (PubMed).

Fukata, Adesnik, Iwanaga, Bredt, Nicoll, Fukata: "Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission." in: Science (New York, N.Y.), Vol. 313, Issue 5794, pp. 1792-5, (2006) (PubMed).

Gu, Gibert, Wirth, Elischer, Bloch, Meyer, Steinlein, Begemann: "Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders." in: Molecular biology and evolution, Vol. 22, Issue 11, pp. 2209-16, (2005) (PubMed).

Chernova, Somerville, Cowell: "A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors." in: Oncogene, Vol. 17, Issue 22, pp. 2873-81, (1999) (PubMed).

Synonyms and alternative names related to Leucine-Rich, Glioma Inactivated 1

leucine rich glioma inactivated 1 (LGI1), leucine-rich repeat LGI family, member 1 (Lgi1), leucine-rich, glioma inactivated 1 (Lgi1), leucine-rich, glioma inactivated 1 (LGI1), leucine-rich, glioma inactivated 1 (lgi1), leucine rich glioma inactivated 1 (Lgi1), leucine-rich, glioma inactivated 1b (lgi1b), leucine-rich, glioma inactivated 1a (lgi1a), ADLTE, ADPAEF, ADPEAF, BB130740, EPITEMPIN, EPT, ETL1, fb78h12, IB1099, LGIa, MGC146600, wu:fb78h12, zgc:65886

Protein level used designations for Leucine-Rich, Glioma Inactivated 1

  • epitempin-1
  • leucine-rich glioma-inactivated protein 1
  • leucine-rich, glioma inactivated 1
  • leucine-rich repeat LGI family, member 1
  • putative leucine-rich glioma inactivated 1
  • polymorphic marker clone YB07
  • leucine-rich glioma-inactivated protein 1-like
  • leucine-rich, glioma inactivated 1a
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