PCSK9 ELISA 试剂盒
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- 抗原 See all PCSK9 ELISA试剂盒
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 156 pg/mL - 10000 pg/mL
- 最低检测浓度
- 156 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: Convertase subtilisin/kexin type 9 preproprotein, FH3, HCHOLA3, Hypercholesterolemia autosomal dominant 3, LDLCQ1, NARC 1, NARC-1, NARC1, Neural apoptosis regulated convertase 1, Neural apoptosis-regulated convertase 1, PC 9, PC9, PCSK 9, PCSK9, PCSK9_HUMAN, Proprotein convertase 9, Proprotein convertase PC9, Proprotein convertase subtilisin/kexin type 9, PSEC0052, Subtilisin/kexin like protease PC9, Subtilisin/kexin-like protease PC9
Background: Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.
Gene Name: PCSK9
Production: Natural and recombinant human PCSK9. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: S153-Q692
- Top Product
- Discover our top product PCSK9 ELISA Kit
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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA Kit
PCSK9 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cell Culture Supernatant, Plasma, Serum
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 人 Colorimetric Sandwich ELISA 0.63 ng/mL - 40 ng/mL Cell Culture Supernatant, Plasma, Serum
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 人 Colorimetric Competition ELISA 0.45 ng/mL - 30 ng/mL Plasma, Serum, Tissue Homogenate
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 大鼠 Colorimetric Competition ELISA 93.75 pg/mL - 6000 pg/mL Plasma, Serum, Tissue Homogenate
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 大鼠 Colorimetric Sandwich ELISA 3.12 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 小鼠 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma, Serum
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 豚鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 兔 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Plasma, Serum
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA KitPCSK9 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human PCSK9 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human PCSK9 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 156pg/mL-10,000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all PCSK9 ELISA试剂盒
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
- 别名
- PCSK9 (PCSK9 产品)
- 别名
- FH3 ELISA Kit, HCHOLA3 ELISA Kit, LDLCQ1 ELISA Kit, NARC-1 ELISA Kit, NARC1 ELISA Kit, PC9 ELISA Kit, AI415265 ELISA Kit, AI747682 ELISA Kit, Narc1 ELISA Kit, proprotein convertase subtilisin/kexin type 9 ELISA Kit, proprotein convertase subtilisin/kexin type 9 L homeolog ELISA Kit, PCSK9 ELISA Kit, pcsk9.L ELISA Kit, pcsk9 ELISA Kit, Pcsk9 ELISA Kit
- 基因ID
- 255738
- NCBI登录号
- NP_777596
- UniProt
- Q8NBP7
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