APP ELISA 试剂盒
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- 抗原 See all APP ELISA试剂盒
- APP (Amyloid beta (A4) Precursor Protein (APP))
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 312 pg/mL - 20000 pg/mL
- 最低检测浓度
- 312 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: A4 amyloid protein, A4|A4_HUMAN, AAA, ABETA, ABPP, AD 1, Alzheimer disease 1, Alzheimer disease amyloid protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform a, Amyloid of aging and alzheimer disease, APP I, Beta amyloid peptide, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PreA4, Protease nexin II
Background: Amyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.
Gene Name: APP
Production: Natural and recombinant human APP. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: L18-L688
- Top Product
- Discover our top product APP ELISA Kit
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Amyloid beta (A4) Precursor Protein (APP) ELISA Kit
APP 适用: 人 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cerebrospinal Fluid, Plasma, Serum
Amyloid beta (A4) Precursor Protein (APP) ELISA KitWide Range APP 适用: 人 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cerebrospinal Fluid, Plasma, Serum
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP 适用: 小鼠 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitWide Range APP 适用: 大鼠 Colorimetric Sandwich ELISA 1.25 ng/mL - 80 ng/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP 适用: 大鼠 Colorimetric Sandwich ELISA 78.12 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP 适用: 人 Colorimetric Sandwich ELISA 0.25-16 ng/mL Cell Culture Cells, Plasma, Serum
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20000pg/mL, 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human APP standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human APP standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 312pg/mL-20000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all APP ELISA试剂盒
- APP (Amyloid beta (A4) Precursor Protein (APP))
- 别名
- APP (APP 产品)
- 别名
- AAA ELISA Kit, ABETA ELISA Kit, ABPP ELISA Kit, AD1 ELISA Kit, APPI ELISA Kit, CTFgamma ELISA Kit, CVAP ELISA Kit, PN-II ELISA Kit, PN2 ELISA Kit, aaa ELISA Kit, abeta ELISA Kit, abpp ELISA Kit, ad1 ELISA Kit, appi ELISA Kit, ctfgamma ELISA Kit, cvap ELISA Kit, pn2 ELISA Kit, APP ELISA Kit, APP-like ELISA Kit, APPL ELISA Kit, Abeta ELISA Kit, BcDNA:GH04413 ELISA Kit, CG7727 ELISA Kit, Dmel\\CG7727 ELISA Kit, EG:65F1.5 ELISA Kit, appl ELISA Kit, Abpp ELISA Kit, Adap ELISA Kit, Ag ELISA Kit, Cvap ELISA Kit, E030013M08Rik ELISA Kit, betaApp ELISA Kit, app ELISA Kit, wu:fj34d10 ELISA Kit, wu:fk65e12 ELISA Kit, zgc:85740 ELISA Kit, amyloid beta precursor protein ELISA Kit, amyloid beta (A4) precursor protein ELISA Kit, beta amyloid protein precursor-like ELISA Kit, amyloid beta (A4) precursor protein a ELISA Kit, amyloid beta precursor protein L homeolog ELISA Kit, APP ELISA Kit, app ELISA Kit, Appl ELISA Kit, App ELISA Kit, appa ELISA Kit, app.L ELISA Kit
- 基因ID
- 351
- NCBI登录号
- NP_000475
- UniProt
- P05067
- 途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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