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SERPINA5 ELISA 试剂盒

SERPINA5 适用: 人 AA 26-406 Colorimetric Sandwich ELISA 156 pg/mL - 10000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Urine
产品编号 ABIN5692228
发货至: 中国
  • 抗原 See all SERPINA5 ELISA试剂盒
    SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
    抗原表位
    AA 26-406
    适用
    • 4
    • 2
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    • 1
    • 1
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    156 pg/mL - 10000 pg/mL
    最低检测浓度
    156 pg/mL
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Serpin A5/PAI3. 96wells/kit, with removable strips.
    品牌
    PicoKine™
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Urine
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: E26-P406
    灵敏度
    < 10 pg/mL
    组件
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
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  • 实验时间
    15 min
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all SERPINA5 ELISA试剂盒
    SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
    别名
    Serpina5 (SERPINA5 产品)
    别名
    4933415L04 ELISA Kit, PAI-3 ELISA Kit, Pci ELISA Kit, PAI3 ELISA Kit, PCI ELISA Kit, PCI-B ELISA Kit, PLANH3 ELISA Kit, PROCI ELISA Kit, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 ELISA Kit, serpin family A member 5 ELISA Kit, serine (or cysteine) peptidase inhibitor, clade A, member 5 ELISA Kit, plasma serine protease inhibitor ELISA Kit, SPIA5 ELISA Kit, SERPINA5 ELISA Kit, Serpina5 ELISA Kit, LOC480424 ELISA Kit
    背景

    Synonyms: Plasma serine protease inhibitor, Acrosomal serine protease inhibitor, Plasminogen activator inhibitor 3, PAI-3, PAI3, Protein C inhibitor, PCI, Serpin A5, SERPINA5, PCI, PLANH3, PROCI

    Tissue Specificity: Predominantly expressed in the epithelium of seminal vesicles. Expressed in the proximal tubular epithelium of the kidney. Expressed in the superficial and more differentiated epidermal keratinocytes of the skin. Expressed in megakaryocytes and platelets. Expressed poorly in kidney tumor cells compared to non tumor kidney tissues. Expressed in spermatozoa. Present in very high concentration in seminal plasma. Present in high concentration in plasma, synovial and Graaf follicle fluids. Present in low concentration in breast milk and in amniotic fluids. Present in very low concentration in urine, cerebrospinal fluids, saliva and tears (at protein level). Strongly expressed in liver. Expressed in kidney, spleen, pancreas, skeletal muscle, heart, testes, ovary, interstitial Leydig cells, epididymal glands, seminal vesicles and prostate.

    Background: Protein C inhibitor (PCI), also known as SERPINA5, is serine protease inhibitor of serpin type that is found in most tissues and fluids, including blood plasma, seminal plasma and urine of human. It is a 52kD glycoprotein and belongs to serine protease inhibitor (Serpin) super family of protein. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. This gene is mapped on the q arm of chromosome 14.

    Cellular Localisation: Secreted, extracellular space
    UniProt
    P05154
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