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ENPP2 ELISA 试剂盒

ENPP2 适用: 人 AA 36-863 Colorimetric Sandwich ELISA 625 pg/mL - 40000 pg/mL Cell Culture Supernatant, Milk, Plasma (heparin), Serum, Urine
产品编号 ABIN5692213
发货至: 中国
  • 抗原 See all ENPP2 ELISA试剂盒
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    抗原表位
    AA 36-863
    适用
    • 3
    • 2
    • 1
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    625 pg/mL - 40000 pg/mL
    最低检测浓度
    625 pg/mL
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Autotaxin. 96wells/kit, with removable strips.
    品牌
    PicoKine™
    样品类型
    Cell Culture Supernatant, Milk, Plasma (heparin), Serum, Urine
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: A36-I863
    灵敏度
    < 10 pg/mL
    组件
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
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  • 实验时间
    15 min
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all ENPP2 ELISA试剂盒
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    别名
    ENPP2 (ENPP2 产品)
    别名
    ATX ELISA Kit, ATX-X ELISA Kit, AUTOTAXIN ELISA Kit, LysoPLD ELISA Kit, NPP2 ELISA Kit, PD-IALPHA ELISA Kit, PDNP2 ELISA Kit, Npps2 ELISA Kit, PD-Ialpha ELISA Kit, Pdnp2 ELISA Kit, MGC132047 ELISA Kit, atx ELISA Kit, zgc:63550 ELISA Kit, autotaxin ELISA Kit, enpp2 ELISA Kit, enpp2a ELISA Kit, enpp2b ELISA Kit, ectonucleotide pyrophosphatase/phosphodiesterase 2 ELISA Kit, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog ELISA Kit, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog ELISA Kit, ENPP2 ELISA Kit, Enpp2 ELISA Kit, enpp2 ELISA Kit, enpp2.L ELISA Kit, enpp2.S ELISA Kit
    背景

    Synonyms: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, ENPP2, ATX, PDNP2

    Tissue Specificity: Predominantly expressed in brain, placenta, ovary, and small intestine. Expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. Expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. Not detected in leukocytes. Isoform 1 is more highly expressed in peripheral tissues than in the central nervous system (CNS). Adipocytes only express isoform 1. Isoform 3 is more highly expressed in the brain than in peripheral tissues.

    Background: Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2), is an enzyme that in humans is encoded by the ENPP2 gene. The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localisation: Secreted.
    UniProt
    Q13822
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