人 Rena-strip Kit

ABIN5665116 产品详细信息, 供应商: Log in to see
抗原
  • HAVCR
  • HAVCR-1
  • KIM-1
  • KIM1
  • TIM
  • TIM-1
  • TIM1
  • TIMD-1
  • TIMD1
  • Kim1
  • AI503787
  • Tim1
  • Timd1
  • hepatitis A virus cellular receptor 1
  • HAVCR1
  • Havcr1
适用

7
6
6
1
1
1
1
1
1
应用范围
Detection (D), Lateral Flow (LF)
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原理 The Rena-strip™ test is a single-use, qualitative, or quantitative (with reader), lateral flow assay for the detection of KIM-1 in human urine.
样品类型 Urine
Analytical Method Qualitative and Quantitative
产品特性 The Human Rena-strip test is a 15-minute qualitative (or quantitative with optional reader) lateral flow assay. Human urine samples are added to the cassette and results can be read within 15 minutes.
组件 Human Rena-strip cassettes in white foil pouches with dessicant, 25 cassettes
背景 KIM-1 is a type I trans-membrane structural glycoprotein located in the renal proximal tubule epithelial cells. These cells undergo regeneration after various forms of injury and shed KIM-1 antigen into the urine. Thus, urinary KIM-1 is an early and specific biomarker for tubular kidney injury. KIM-1 has become widely recognized by many organizations and agencies, including the FDA, as an excellent biomarker in pre-clinical studies to monitor acute kidney tubular toxicity by identifying adverse reactive drugs and therapeutic agents in drug development.
Kidney injury caused by therapeutic agents and drug induction is a common type of injury requiring appropriate monitoring and intervention. Current standards using blood urea nitrogen and creatinine are considered late indicators of kidney injury and are often non-specific. KIM-1 has been shown continually to outperform traditional biomarkers of kidney injury in preclinical biomarker studies. The detection of KIM-1 can occur in as little as six hours post injection of an agent known to cause kidney injury.
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
储存条件 RT
有效期 24 months
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