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- 抗原 See all ACVRL1 ELISA试剂盒
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- 抗原表位
- AA 23-119
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse ALK-1/ACVRL1
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: D23-P119 - 交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
- Top Product
- Discover our top product ACVRL1 ELISA Kit
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Activin A Receptor Type II-Like 1 (ACVRL1) ELISA Kit
ACVRL1 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate
Activin A Receptor Type II-Like 1 (ACVRL1) ELISA KitACVRL1 适用: 人 AA 22-118 Colorimetric Sandwich ELISA
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all ACVRL1 ELISA试剂盒
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- 别名
- Acvrl1 (ACVRL1 产品)
- 别名
- ACVRL1 ELISA Kit, vgb ELISA Kit, alk1 ELISA Kit, zehn1109 ELISA Kit, hm:zehn1109 ELISA Kit, ACVRLK1 ELISA Kit, ALK-1 ELISA Kit, ALK1 ELISA Kit, HHT ELISA Kit, HHT2 ELISA Kit, ORW2 ELISA Kit, SKR3 ELISA Kit, TSR-I ELISA Kit, R-3 ELISA Kit, R3 ELISA Kit, SETHKIR ELISA Kit, AI115505 ELISA Kit, AI427544 ELISA Kit, Acvrlk1 ELISA Kit, Alk1 ELISA Kit, activin A receptor like type 1 ELISA Kit, activin A receptor type II-like 1 ELISA Kit, activin A receptor, type II-like 1 ELISA Kit, ACVRL1 ELISA Kit, acvrl1 ELISA Kit, Acvrl1 ELISA Kit
- 背景
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Protein Function: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. .
Background: Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. It is also known as activin receptor-like kinase 1, or ALK1. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Synonyms: Serine/threonine-protein kinase receptor R3,SKR3,2.7.11.30,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,Acvrl1,Acvrlk1, Alk-1,
Full Gene Name: Serine/threonine-protein kinase receptor R3
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. - UniProt
- Q61288
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