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COL18A1 ELISA 试剂盒

COL18A1 适用: 大鼠 AA 1591-1774 Colorimetric Sandwich ELISA
产品编号 ABIN5510629
发货至: 中国
  • 抗原 See all COL18A1 ELISA试剂盒
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    抗原表位
    AA 1591-1774
    适用
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Endostatin
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO
    Immunogen sequence: H1591-K1774
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    Featured
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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all COL18A1 ELISA试剂盒
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    别名
    Endostatin (COL18A1 产品)
    别名
    KNO ELISA Kit, KNO1 ELISA Kit, KS ELISA Kit, cb371 ELISA Kit, cb529 ELISA Kit, fc96d06 ELISA Kit, sb:cb529 ELISA Kit, wu:fb47h10 ELISA Kit, wu:fb77g12 ELISA Kit, wu:fc50f04 ELISA Kit, wu:fc96d06 ELISA Kit, wu:fk02h12 ELISA Kit, kno ELISA Kit, kno1 ELISA Kit, collagen type XVIII alpha 1 chain ELISA Kit, collagen type XVIII alpha 1 chain a ELISA Kit, collagen, type XVIII, alpha 1 ELISA Kit, collagen type XVIII alpha 1 ELISA Kit, COL18A1 ELISA Kit, col18a1a ELISA Kit, Col18a1 ELISA Kit, col18a1 ELISA Kit
    物质类
    Chemical
    背景

    Background: Endostatin is a naturally-occurring 20- kDa C-terminal fragment derived from type XVIII collagen. It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. And It is produced by proteolytic cleavage of collagen XVIII, a member of the multiplexin family that is characterized by interruptions in the triple helix creating multiple domains, by proteases such as cathepsins. Using a genomic clone as a probe for fluorescence in situ hybridization, Endostatin was mapped the COL18A1 gene to 21q22.3. By immunoprecipitation analysis using membrane fractions of human mammary epithelial cells, It showed that endostatin specifically bound to cell surface nucleolin with high affinity. Blockage of nucleolin with neutralizing antibody or knockdown of nucleolin by RNA interference countered the antiendothelial activity of endostatin and abrogated its antiangiogenic and antitumor activity in vivo.

    Synonyms: Collagen type XVIII, alpha (I) chain ,Col18a1 ,col18a1 ,

    Full Gene Name: collagen, type XVIII, alpha 1

    UniProt
    Q9WUW5
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