Quick Overview for SensoLyte® 490 MMP-12 Assay Kit (ABIN1882513)
抗原
See all MMP12 试剂盒检测方法
应用范围
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                                            品牌
- SensoLyte®
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                                            产品特性
- The SensoLyte® 490 MMP-12 Assay Kit is a complete assay system designed to continuously analyze MMP-12 activity or to screen for MMP-12 inhibitors by using a fluorogenic MMP-12 substrate.
 
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                                            说明
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                        FRET-based Assay Kit 
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                                            限制
- 仅限研究用
 
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                                            注意事项
- Protect Components A and B from light.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store all components at -20 °C. Components D and E can be stored at 4 °C for convenience.
 
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                                            : "Expression of matrix metalloproteinase-12 in aortic dissection."    in: BMC cardiovascular disorders, Vol. 13, pp. 34, (2013)         (PubMed).        
 : "Inhibitory effect of Chinese green tea on cigarette smoke-induced up-regulation of airway neutrophil elastase and matrix metalloproteinase-12 via antioxidant activity." in: Free radical research, Vol. 46, Issue 9, pp. 1123-9, (2012) (PubMed).
 : "Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 5, pp. L679-90, (2011) (PubMed).
 : "Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition." in: Cancer research, Vol. 69, Issue 18, pp. 7252-61, (2009) (PubMed).
 : "A Phos-tag-based fluorescence resonance energy transfer system for the analysis of the dephosphorylation of phosphopeptides." in: Analytical biochemistry, Vol. 388, Issue 2, pp. 235-41, (2009) (PubMed).
 : "Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice." in: Molecular genetics and metabolism, Vol. 94, Issue 3, pp. 298-304, (2008) (PubMed).
 : "Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 6, pp. L1035-42, (2008) (PubMed).
 : "Elevated MMP-12 protein levels in induced sputum from patients with COPD." in: Thorax, Vol. 61, Issue 3, pp. 196-201, (2006) (PubMed).
 
 
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                                            : "Expression of matrix metalloproteinase-12 in aortic dissection."    in: BMC cardiovascular disorders, Vol. 13, pp. 34, (2013)         (PubMed).        
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    - MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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                                            别名
- MMP-12
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                                            背景
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is implicated in the pathology of many diseases such as emphysema, aortic lesions and cancer. It has recently been shown to play a role in the pathogenesis of rheumatoid arthritis.
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