anti-SRC (SRC) 抗体产品概述

Full name:: anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) 抗体 (SRC)

在www.antibodies-online.cn可供477 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) 抗体的31不同的供货商。再加上，我们可以发SRC 蛋白 (21) 和 SRC 试剂盒 (16)和数多这个蛋白质的别的产品。总共540 SRC产品已列进来了。

别名:: ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

列出全部抗体	基因	基因ID	UniProt
	SRC	20779	P05480
	SRC	6714	P12931
	SRC	83805
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Human Polyclonal SRC Primary Antibody for FACS, IF - ABIN1881833 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
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Human Polyclonal SRC Primary Antibody for WB - ABIN1881832 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
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Human Polyclonal SRC Primary Antibody for IHC - ABIN967081 : David-Dufilho, Millanvoye-Van Brussel, Topal, Walch, Brunet, Rendu: Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. in The Journal of biological chemistry 2005 (PubMed)
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Human Polyclonal SRC Primary Antibody for IHC - ABIN967082 : Parker, Mardon, Lebo, Varmus, Bishop: Isolation of duplicated human c-src genes located on chromosomes 1 and 20. in Molecular and cellular biology 1985 (PubMed)
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Human SRC Primary Antibody for IHC - ABIN967080 : Pyper, Bolen: Identification of a novel neuronal C-SRC exon expressed in human brain. in Molecular and cellular biology 1990 (PubMed)
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Human Monoclonal SRC Primary Antibody for ELISA, WB - ABIN1724696 : Li, Aurandt, Jürgensen, Jürgense, Rao, Guan: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5. in Journal of cell science 2005 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177179 : Alvarez, Kantarjian, Cortes: The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors. in Cancer 2006 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177181 : Arias-Salgado, Lizano, Sarkar, Brugge, Ginsberg, Shattil: Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177180 : Frame: Newest findings on the oldest oncogene; how activated src does it. in Journal of cell science 2004 (PubMed)
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Human Monoclonal SRC Primary Antibody for IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. in FEBS letters 2011 (PubMed)
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更多抗SRC的相互作用对抗体

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

Src kinase (显示 CSK 抗体) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
RANKL (显示 TNFSF11 抗体) and Src has an unrecognized role in osteocyte survival.
These interactions are required for SRC-induced activation of VAV (显示 VAV1 抗体) and the subsequent engagement of a JIP1 (显示 MAPK8IP1 抗体)-tethered JNK (显示 MAPK8 抗体) signaling module.
Elevated retinoic acid-inducible gene 1 (显示 RARRES3 抗体) (RIG-I (显示 DDX58 抗体)) modulated the interaction of activated proto-oncogene c-Src (Src) and STAT3 (显示 STAT3 抗体) by competitive binding to STAT3 (显示 STAT3 抗体).
Cbl, Cbl-b, and Cbl-c have a role in protecting mammary epithelial cellsfrom proteotoxic stress-induced cell death by promoting turnover of active c-Src
unlike c-fos-/- mice, c-src-/- mice demonstrated activated, mature osteoblasts, and parallel layers of cement lines in the superficial bone matrix, indicating the new bones were piled up to older bone.
TM, especially TME45, maintains vascular integrity, at least in part, via Src signaling.
We conclude that pp60(Src) can directly inhibit DDAH (显示 DDAH2 抗体) II and this is involved in the increased ADMA levels that enhance eNOS (显示 NOS3 抗体) uncoupling during the development of acute lung injury (ALI).
Ambra1 (显示 AMBRA1 抗体) binds to both FAK (显示 PTK2 抗体) and Src in cancer cells. When FAK (显示 PTK2 抗体) is present, Ambra1 (显示 AMBRA1 抗体) is recruited to focal adhesions, promoting FAK (显示 PTK2 抗体)-regulated cancer cell direction-sensing and invasion. However, when Ambra1 (显示 AMBRA1 抗体) cannot bind to FAK (显示 PTK2 抗体), abnormally high levels of phospho-Src and phospho-FAK (显示 PTK2 抗体) accumulate at focal adhesions, positively regulating adhesion and invasive migration.
Thus we propose that Cx43 (显示 GJA1 抗体) might enhance the activation of Nrf2 (显示 NFE2L2 抗体)/ARE pathway by means of inhibiting c-Src activity to hinder the nuclear export of Nrf2 (显示 NFE2L2 抗体), and then reduce expression of FN, ICAM-1 (显示 ICAM1 抗体) and TGF-b1, ultimately attenuating renal fibrosis in diabetes.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

Src overexpression alone activated the Jun N-terminal Kinase (JNK (显示 MAPK8 抗体)) signalling pathway to promote actin (显示 ACTB 抗体) cytoskeletal and cell polarity defects and drive apoptosis in in a whole epithelial tissue context in the Drosophila eye, whereas, in cooperation with RasACT, JNK (显示 MAPK8 抗体) led to a loss of differentiation and an invasive phenotype.
Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo
that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction
Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.
a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.
Data show that the actin-Capping Protein (显示 TMOD4 抗体) (CP) alphabeta heterodimer, which regulates actin (显示 ACTB 抗体) filament (F-actin (显示 ACTB 抗体)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (显示 MAPK8 抗体) activation.
Dumbfounded/Neph1 (显示 NEPH1 抗体), a key diaphragm constituent, is a target of the Src kinase (显示 CSK 抗体) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (显示 NEPH1 抗体) tyrosine phosphorylation.
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.
E4orf4 has a role in inducing PP2A (显示 PPP2R2B 抗体)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster
Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

This study shows that Leu33Pro polymorphism of integrin beta 3 (显示 ITGB3 抗体) modulates platelet Src pY418 and focal adhesion kinase pY397 phosphorylation in response to abnormally high shear stress. Whereas physiological shear stress does not affect platelet signaling, abnormally high-shear stress considerably elevates Src and FAK (显示 PTK2 抗体) phosphorylation in both Pro33 and Leu33 platelets.
High SRC expression is associated with lung adenocarcinoma.
While activation in c-Src is strictly controlled by ATP-binding and phosphorylation, the authors find that activating conformational transitions are spontaneously sampled in Hsp90 (显示 HSP90 抗体)-dependent Src mutants.
High SRC expression is associated with gastric cancer cell migration.
Src kinase (显示 CSK 抗体) mediates UV-induced TRPV1 (显示 TRPV1 抗体) trafficking into cell membrane in HaCaT keratinocytes.
Src kinase (显示 CSK 抗体) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
Src and Aurora-A (显示 AURKA 抗体) interact upon Golgi ribbon fragmentation; Src phosphorylates Aurora-A (显示 AURKA 抗体) at tyrosine 148 and this specific phosphorylation is required for Aurora-A (显示 AURKA 抗体) localization at the centrosomes.
Study demonstrated that c-Src contributed to hypoxic microenvironment-rendered paclitaxel resistance in human epithelial ovarian cancer cells by G2/M phase arrest deterioration, and through c-Src suppression, FV-429 was capable of reversing the resistance by blocking c-Src/Stat3 (显示 STAT3 抗体)/HIF-1alpha (显示 HIF1A 抗体) pathway.
Data demonstrated that the Src/Fn14 (显示 TNFRSF12A 抗体)/NF-kappaB (显示 NFKB1 抗体) axis plays a critical role in NSCLC metastasis.
Results suggest that Src promotes EGF (显示 EGF 抗体)-stimulated EMT (显示 ITK 抗体) and migration by upregulation of ZEB1 (显示 ZEB1 抗体) and ZEB2 (显示 ZEB2 抗体) through AKT (显示 AKT1 抗体) signaling pathway in gastric cancer cells.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

RhoA (显示 RHOA 抗体) and membrane fluidity mediates the spatially polarized Src/FAK (显示 PTK2 抗体) activation in response to shear stress.
AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.
The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.
src has a role in activation of 5'-AMP (显示 TMPRSS5 抗体)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells
results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network
These results suggest that TGF-beta1 (显示 TGFB1 抗体)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (显示 PTK2 抗体)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

The findings are consistent with previous studies that indicate a link between Na,K-ATPase (显示 ATP1A1 抗体) activity and SFK signaling.
Src kinase (显示 CSK 抗体) mediates hypoxia-induced caspase-1 (显示 CASP1 抗体) activation in the cerebral cortex of newborn piglets
Expression of mutant alpha1 Na/K-ATPase (显示 ATP1A1 抗体) defective in conformational transition attenuates Src-mediated signal transduction
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC 抗原简介

Antigen Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) 抗体
uncharacterized LOC5574802 (LOC5574802) 抗体
proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) 抗体
Rous sarcoma oncogene (Src) 抗体
Src oncogene at 64B (Src64B) 抗体
SRC proto-oncogene, non-receptor tyrosine kinase (Src) 抗体

ASV 抗体
AW259666 抗体
c-Src 抗体
C-src1 抗体
CG7524 抗体
D-src 抗体
D-Src64B 抗体
Dmel\CG7524 抗体
DmHD-358 抗体
Dm SRC1 抗体
dsrc 抗体
Dsrc64 抗体
Dsrc64B 抗体
HD-358 抗体
MRE5 抗体
p60-Src 抗体
PP60C-SCR 抗体
pp60c-src 抗体
SDR 抗体
src 抗体
SRC1 抗体
src64 抗体
SRC 64B 抗体
src64b 抗体

Protein level used designations for SRC

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , proto-oncogene tyrosine-protein kinase SRC proto-oncogene tyrosine-protein kinase src neuronal proto-oncogene tyrosine-protein kinase Src p60-Src proto-oncogene c-Src CG7524-PB CG7524-PC CG7524-PD CG7524-PE CG7524-PF CG7524-PG CG7524-PH CG7524-PI CG7524-PJ Src proto oncogene sequence Src64B-PB Src64B-PC Src64B-PD Src64B-PE Src64B-PF Src64B-PG Src64B-PH Src64B-PI Src64B-PJ mRNA-like ncRNA in embryogenesis 5 proto-oncogene tyrosine-protein kinase Src protooncogene SRC, Rous sarcoma tyrosine kinase pp60c-src tyrosine-protein kinase SRC-1 Rous sarcoma oncogene c-Src pp60c-src tyrosine protein kinase c-src tyrosine protein kinase pp60-c-src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog src oncogene v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog non-tyrosine protein kinase

GENE ID	SPECIES
458229	Pan troglodytes
5574802	Aedes aegypti
6043642	Culex quinquefasciatus
20779	Mus musculus
48973	Drosophila melanogaster
6714	Homo sapiens
83805	Rattus norvegicus
485864	Canis lupus familiaris
535742	Bos taurus
100154503	Sus scrofa
396442	Gallus gallus

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