anti-小鼠 IL4 Receptor 抗体 for ELISpot (Detection)

Recommended IL4 Receptor Antibody (supplied by: Log in to see )

抗原
Interleukin 4 Receptor (IL4R) 抗体
  • IL4R
  • il-4ra
  • zgc:113063
  • CD124
  • IL-4RA
  • IL4RA
  • Il4ra
  • IL4
  • Il4r
  • interleukin 4 receptor
  • interleukin 4 receptor, tandem duplicate 1
  • interleukin 4 receptor, alpha
  • IL4R
  • il4r.1
  • Il4r
  • Il4ra
适用
小鼠
128
59
10
宿主
大鼠
74
64
24
14
1
克隆类型
单克隆
标记
This IL4 Receptor antibody is un-conjugated
11
9
5
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
1
应用范围
ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
96
57
57
35
27
12
12
6
5
4
3
3
3
2
2
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

产品编号 ABIN2664185
产品在该地区无法提供。
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2664186 ELISA (Detection) ELISPOT (Detection) ICFC Rat IgG2b kappa Log in to see I015F8 3

General

抗原 Interleukin 4 Receptor (IL4R) 抗体
适用 小鼠
(128), (59), (10)
宿主 大鼠
(74), (64), (24), (14), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This IL4 Receptor antibody is un-conjugated
(11), (9), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
应用范围 ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
(96), (57), (57), (35), (27), (12), (12), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3个引用可参考
Supplier Log in to see

IL4 Receptor抗体详情

IL4 Receptor目标详情 使用细节 贮存及处理 References for anti-IL4 Receptor antibody (ABIN2664185) 图像
纯化方法 The antibody was purified by affinity chromatography.
克隆位点 I015F8
亚型 IgG2b kappa

IL4 Receptor目标详情

IL4 Receptor抗体详情 使用细节 贮存及处理 References for anti-IL4 Receptor antibody (ABIN2664185) 图像 回页首
抗原
别名 CD124 (IL4R Antibody 摘要)
背景 CD124, a subunit of IL-4R, is a 140 kD transmembrane glycoprotein. It associates with either the common γ-chain (CD132) to form the type I IL-4R complex, which specifically binds IL-4, or with IL-13Ra1 to form the type II IL-4R heterodimeric complex, which binds and transduces signals from either IL-4 or IL-13. A truncated form of IL-4Rα exists in soluble form in biological fluids. CD124 is expressed on mouse late precursors and mature B cells, T cells, monocytes, and has low expression on granulocytes. In B cells, CD124 can bind IL-4 and IL-13 and regulate IgE antibody production. In T cells, the type I IL-4R (IL-4R/gC) is mostly responsible for Th2 cell expansion by mediating IL-4-dependent activation of the transcription factors in hematopoietic cells. The type II IL-4R (IL-4R/IL-13Ra1) is the main route for nonhematopoietic cell responses to IL-4 or IL-13.
途径 JAK/STAT Signaling, Positive Regulation of Immune Effector Process

使用细节

IL4 Receptor抗体详情 IL4 Receptor目标详情 贮存及处理 References for anti-IL4 Receptor antibody (ABIN2664185) 图像 回页首
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用

贮存及处理

IL4 Receptor抗体详情 IL4 Receptor目标详情 使用细节 References for anti-IL4 Receptor antibody (ABIN2664185) 图像 回页首
浓度 0.5 mg/mL
缓冲液 Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL4 Receptor antibody (ABIN2664185)

IL4 Receptor抗体详情 IL4 Receptor目标详情 使用细节 贮存及处理 图像 回页首
背景

Gilmour, Lavender: "Control of IL-4 expression in T helper 1 and 2 cells." in: Immunology, Vol. 124, Issue 4, pp. 437-44, 2008

Kashiwada, Giallourakis, Pan, Rothman: "Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6382-7, 2001

Hage, Sebald, Reinemer: "Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface." in: Cell, Vol. 97, Issue 2, pp. 271-81, 1999

图像

IL4 Receptor抗体详情 IL4 Receptor目标详情 使用细节 贮存及处理 References for anti-IL4 Receptor antibody (ABIN2664185) 回页首
厂商提供的图像
Flow Cytometry (FACS) image for anti-Interleukin 4 Receptor (IL4R) antibody (ABIN2664185) anti-Interleukin 4 Receptor (IL4R) antibody
Flow Cytometry (FACS) image for anti-Interleukin 4 Receptor (IL4R) antibody (ABIN2664185) anti-Interleukin 4 Receptor (IL4R) antibody (Image 2)