anti-IL21 Receptor 抗体

蛋白简介

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with IL21 Receptor (IL21R)

• interleukin 21 receptor (IL21R) 抗体
• interleukin 21 receptor, tandem duplicate 1 (il21r.1) 抗体
• interleukin 21 receptor (Il21r) 抗体

• CD360 抗体
• il-21ra.a 抗体
• IL21R 抗体
• NILR 抗体

Protein level used designations for IL21R

interleukin-21 receptor , interleukin 21 receptor , interleukin 21 receptor alpha.a , IL-21 receptor , novel interleukin receptor , IL-21R , LR-beta , NR8 , lymphocyte receptor beta , novel cytokine receptor 8