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|抗原||Interleukin 12 Receptor beta 1 (IL12RB1) 抗体|
|抗原表位||AA 624-662, C-Term 其他选择|
|标记||This IL12RB1 antibody is un-conjugated 其他选择|
Western Blotting (WB)
|Supplier||Log in to see|
IL12RB1抗体详情IL12RB1目标详情 使用细节 贮存及处理 图像
|原理||Rabbit IgG polyclonal antibody for Interleukin-12 receptor subunit beta-1 (IL12RB1) detection. Tested with WB in Human.|
|序列||DKGERTEPLE KTELPEGAPE LALDTELSLE DGDRCKAKM|
|交叉反应 （详细）||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Interleukin-12 receptor subunit beta-1 (IL12RB1) detection. Tested with WB in Human.
Gene Name: interleukin 12 receptor subunit beta 1
Protein Name: Interleukin-12 receptor subunit beta-1
|纯化方法||Immunogen affinity purified.|
|免疫原||A synthetic peptide corresponding to a sequence at the C-terminus of human IL12RB1 (624-662aa DKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKAKM).|
|Plasmids, Primers & others|
IL12RB1目标详情IL12RB1抗体详情 使用细节 贮存及处理 图像 回页首
|别名||IL12RB1 (IL12RB1 Antibody 摘要)|
IL12RB1, mapped to 19p13.11, is also known as CD212. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. And this protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
Synonyms: CD212 | IL-12R-beta-1 | IL-12RB1 | IL12RB | Il12rb1 | IMD3 | IMD30 | P42701
|途径||JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation|
使用细节IL12RB1抗体详情 IL12RB1目标详情 贮存及处理 图像 回页首
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
贮存及处理IL12RB1抗体详情 IL12RB1目标详情 使用细节 图像 回页首
|溶解方式||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|缓冲液||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|注意事项||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|注意事项||Avoid repeated freezing and thawing.|
|储存条件||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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