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Mouse (Murine) IL-4 ELISA Kit for Sandwich ELISA - ABIN411300
Wang, Deng, Jiang, Yao: The natural plant product sophocarpine ameliorates dextran sodium sulfate-induced colitis in mice by regulating cytokine balance. in International journal of colorectal disease 2012
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Mouse (Murine) IL-4 ELISA Kit for Sandwich ELISA - ABIN625147
Herrmann, Andreeff, Gruss, Brach, Lübbert, Mertelsmann: Interleukin-4 inhibits growth of multiple myelomas by suppressing interleukin-6 expression. in Blood 1991
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Human IL-4 ELISA Kit for Sandwich ELISA - ABIN411299
Wang, Feng, Shi, Hao, Yang, Zhang, Kong: Silencing of miR155 promotes the production of inflammatory mediators in Guillain-Barré syndrome in vitro. in Inflammation 2013
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Rat (Rattus) IL-4 ELISA Kit for Sandwich ELISA - ABIN411301
Arai, Nomura, Villaret, DeWaal Malefijt, Seiki, Yoshida, Minoshima, Fukuyama, Maekawa, Kudoh: Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. in Journal of immunology (Baltimore, Md. : 1950) 1989
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Rat (Rattus) IL-4 ELISA Kit for Sandwich ELISA - ABIN625203
Arafa, Mohammad, Atteia: Fenugreek seed powder mitigates cadmium-induced testicular damage and hepatotoxicity in male rats. in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2014
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Human IL-4 ELISA Kit for Sandwich ELISA - ABIN625024
Meltzer, Standley: Modeled repetitive motion strain and indirect osteopathic manipulative techniques in regulation of human fibroblast proliferation and interleukin secretion. in The Journal of the American Osteopathic Association 2008
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Mouse (Murine) IL-4 ELISA Kit for Sandwich ELISA - ABIN415512
Mandhane, Shah, Bahekar, Mehetre, Pawar, Bagad, Chidrewar, Rao, Rajamannar: Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. in International archives of allergy and immunology 2009
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Mouse (Murine) IL-4 ELISA Kit for Sandwich ELISA - ABIN625148
Wu, You, Ma, Li, Yuan, Li, Ye, Liu, Yao, Chen, Lai, Yang: Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice. in PLoS ONE 2013
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Chicken IL-4 ELISA Kit for Sandwich ELISA - ABIN364735
Zhang, Huang, Li, Sui, Wang, Liu, Xu, Yan, Song, Li: Identification and Molecular Characterization of Microneme 5 of Eimeria acervulina. in PLoS ONE 2014
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Chicken IL-4 ELISA Kit for Sandwich ELISA - ABIN414103
Lu, Wu, Zhang, Feng, Dong, Chu, Liu, Peng, Liu, Ma, Hou, Tang: Immunopotentiators Improve the Efficacy of Oil-Emulsion-Inactivated Avian Influenza Vaccine in Chickens, Ducks and Geese. in PLoS ONE 2016
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Liver IL-4 mRNA is downregulated in patients with pancreatic cancer and cachexia.
Low IL4 expression is associated with melanoma.
Cytokines (IFNg (显示 IFNG ELISA试剂盒) and IL-4) estimation was done in the blood and NPA samples of cases and blood samples of controls.The mean levels of interleukin-4 in controls (blood), and cases (NPA and blood) were 1280.77, 956.08 and 692.37 pg/ml, respectively (P<0.05).
In this review, we discuss the molecular mechanisms driving IL-4 production in Th2 and Tfh cells.
In this review, we discuss the structural details of IL-4 and IL-4Ralpha subunit and the structural similarities between IL-4 and IL-13 (显示 IL13 ELISA试剂盒). We also describe detailed chemistry of type-I and type-II receptor complexes and their signaling pathways. Furthermore, we elaborate the strength of type-II hetero dimer signals in response to IL-4 and IL-13 (显示 IL13 ELISA试剂盒).
The obtained data demonstrate that the high level of production of IL-1b (显示 IL1B ELISA试剂盒) and IL-4 in GN patients causes hypothyroidism resulting in the formation of nephrotic syndrome.
IL-4 and IL-17 (显示 IL17A ELISA试剂盒) modulate the functional activity of phagocytes in the maternal blood, cord blood, and colostrum of diabetic mother.
Results showed that plasma and mRNA levels of IL-2 (显示 IL2 ELISA试剂盒), IFN-gamma (显示 IFNG ELISA试剂盒), IL-4, and IL-17A (显示 IL17A ELISA试剂盒) in primary immune thrombocytopenia patients did not change significantly after TPO (显示 THPO ELISA试剂盒)-RA treatment, whereas TGF-beta1 (显示 TGFB1 ELISA试剂盒) levels increased remarkably.
Modulation of IL-2 (显示 IL2 ELISA试剂盒), IL-4, IFN-gamma (显示 IFNG ELISA试剂盒) and/or TNF-alpha (显示 TNF ELISA试剂盒) levels, or inhibitors of Erk1/2 (显示 MAPK1/3 ELISA试剂盒) or S6K1 (显示 RPS6KB1 ELISA试剂盒) may be a new approach to prevent BAFF (显示 TNFSF13B ELISA试剂盒)-induced aggressive B-cell malignancies.
There was no significant difference in serum level of IL-4 between children with MPP (Mycoplasma pneumoniae pneumonia)and those with non-MPP. Among children with MPP, we found similar level of IL-4 regardless of the personal and family history of allergy and asthma or the presence of wheezing.
In the lung, surfactant protein A (SP-A (显示 SFTPA1 ELISA试剂盒)) enhanced interleukin-4 (IL-4)-dependent macrophage proliferation and activation, accelerating parasite clearance and reducing pulmonary injury after infection with a lung-migrating helminth. In the peritoneal cavity and liver, C1q enhancement of type 2 macrophage activation was required for liver repair after bacterial infection.
Data, including data from studies using transgenic mice, suggest that over-expression of IL4 (interleukin 4) in thyroid tissue/cells up-regulates expression of Duox1 (dual oxidase 1), Duoxa1 (dual oxidase maturation factor 1), and Slc26a4 (pendrin) in thyroid tissue/cells; expression of Slc5a5 (sodium-iodide symporter) is down-regulated.
NK cells activated by IL-4 in cooperation with IL-15 (显示 IL15 ELISA试剂盒) exhibit distinctive characteristics with enhanced immunologic cytotoxicity.
we defined a molecular mechanism for IL-4 downregulation of involucrin (显示 IVL ELISA试剂盒) in keratinocytes, which may play an important role in the pathogenesis of AD.
In this study, the effect of continuous IL-4 delivery or bioactive implant coating that constitutively releases a protein inhibitor of CCL2 (显示 CCL2 ELISA试剂盒) signaling (7ND) on particle induced osteolysis were studied in the murine continuous femoral intramedullary particle infusion model
T follicular helper (Tfh) cells arise in tumor-draining lymph nodes where they produce an abundance of IL4. Deletion of IL4-expressing Tfh cells improves antitumor immunity, delays tumor growth, and reduces the generation of immunosuppressive myeloid cells in the lymph nodes.
Findings suggest that interleukin 4 (IL-4) affects anti-tumor immunity and constitutes an attractive therapeutic target to reduce immune suppression in the tumor microenvironment.
this study shows that environmental IL-4 plays a role in conditioning early thymic progenitors lineage choice, which would impact T cell development
IL-4 and IL-13 (显示 IL13 ELISA试剂盒) are required to effectively polarize macrophages/dendritic cells to an M2a phenotype and to promote recovery from acute kidney injury.
These observations suggest that IL-4 and IL-13 (显示 IL13 ELISA试剂盒) likely operate through the Heteroreceptor and influence Th17 cells to convert to Th1 (显示 HAND1 ELISA试剂盒) cells and to acquire increased sensitivity to suppression, leading to control of immune-mediated CNS inflammation.
These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma (显示 IFNG ELISA试剂盒) occurring after parturition and an increase in IL-4 production before calving.
IL-4 may play a role in coordinating the adrenal response to inflammatory stress.
T helper (Th) type 2 cell cytokine IL-4 modulates airway contraction by secreting matrix metalloproteinase-1 (显示 MMP1 ELISA试剂盒) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
IL-4- and IL-10 (显示 IL10 ELISA试剂盒)-producing invariant NKT (显示 SLC22A6 ELISA试剂盒) cells inhibit the Th1 (显示 TH1L ELISA试剂盒) cell response, but not the Th17 cell response
IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.
There was no significant difference of IL-4 production between fresh and frozen peripheral blood mononuclear cells.
The endothelium and subendothelium of porcine iliac arteries that are transduced with recombinant pig IL-4 are effectively protected from complement-dependent immediate injury after perfusion with human blood.
unlike in humans and mice, porcine IL-4 blocks antibody and IL-6 (显示 IL6 ELISA试剂盒) secretion and suppresses antigen-stimulated proliferation of B cells
Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 ratio were significantly lower than those exposed to its low concentration.
IL-4 and STAT6 (显示 STAT6 ELISA试剂盒) are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.
The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (显示 TH1L ELISA试剂盒) biased, interferon-gamma (显示 IFNG ELISA试剂盒) production is qualitatively similar to adult horses, and regulatory IL-10 (显示 IL10 ELISA试剂盒) production by T cells is mature.
This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 or IL-5 (显示 IL5 ELISA试剂盒).
Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine genes IL4.
Mycobacterial infections of macaques induce mRNA encoding a variant IL-4 that functions as a growth factor to promote expansion of 4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T effector cells.
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
, B cell growth factor 1
, B_cell stimulatory factor 1
, lymphocyte stimulatory factor 1
, B-cell IgG differentiation factor
, B-cell growth factor 1
, B-cell stimulatory factor 1
, IGG1 induction factor
, B-cell IGG differentiation factor
, Lymphocyte stimulatory factor 1