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|抗原||Interleukin 4 (IL4) 抗体|
|标记||This IL-4 antibody is un-conjugated 其他选择|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
|Supplier||Log in to see|
IL-4抗体详情IL-4目标详情 使用细节 贮存及处理 图像
|免疫原||IL4 antibody was raised in rabbit using highly pure recombinant human IL-4 as the immunogen.|
|Plasmids, Primers & others|
IL-4目标详情IL-4抗体详情 使用细节 贮存及处理 图像 回页首
|别名||IL4 (IL4 Antibody 摘要)|
|背景||IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.|
|分子量||14 kDa (predicted detection band MW)|
|途径||JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation|
使用细节IL-4抗体详情 IL-4目标详情 贮存及处理 图像 回页首
ELISA: 0.5-2 µg/mL, Inhibition: 0.03-0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
贮存及处理IL-4抗体详情 IL-4目标详情 使用细节 图像 回页首
|溶解方式||Reconstitute in sterile water at a concentration of >0.2 mg/mL.|
|缓冲液||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|储存方法||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|