anti-猪 IL-13 抗体 for Western Blotting

Recommended IL-13 Antibody

抗原
Interleukin 13 (IL13) 抗体
  • IL13
  • IL-13
  • P600
  • Il-13
  • L13
  • interleukin 13
  • IL13
  • Il13
适用
猪, 绵羊, 牛
192
81
54
8
6
3
3
2
2
2
1
1
1
宿主

185
61
45
6
2
克隆类型
多克隆
标记
This IL-13 antibody is un-conjugated
37
13
7
6
4
4
2
2
2
2
2
2
1
1
1
1
1
应用范围
ELISA, Western Blotting (WB)
195
161
62
37
30
22
20
17
17
13
11
11
10
9
6
4
3
2
2
2
1
1
1
1
选项

Available images

产品编号 ABIN964711
$ 598.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
4.8929796 ABIN5580733 ELISA WB Rabbit Polyclonal 0
4 ABIN401064 EIA WB Rabbit IgG Polyclonal 1
4 ABIN1102452 ELISA WB Rabbit IgG Polyclonal 0
1 ABIN2290628 ELISA WB Rabbit IgG Polyclonal 0
1 ABIN6334517 IF/ICC IHC IP WB Mouse 0
1 ABIN6032282 IF/ICC IHC IP WB Rabbit Polyclonal 0
-9.18385 ABIN4324497 ELISA WB Rabbit Polyclonal 0

General

抗原 Interleukin 13 (IL13) 抗体
适用 猪, 绵羊, 牛
(192), (81), (54), (8), (6), (3), (3), (2), (2), (2), (1), (1), (1)
宿主
(185), (61), (45), (6), (2)
克隆类型
多克隆
标记 This IL-13 antibody is un-conjugated
(37), (13), (7), (6), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
应用范围 ELISA, Western Blotting (WB)
(195), (161), (62), (37), (30), (22), (20), (17), (17), (13), (11), (11), (10), (9), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Supplier

IL-13抗体详情

IL-13目标详情 使用细节 贮存及处理 图像
特异性 This product was Protein-A purified from monospecific antiserum by chromatography. This antibody is specific for swine IL-13 protein. A BLAST analysis was used to suggest reactivity with IL-13 from swine sources based on 100% homology with the immunizing sequence. The following homologies may indicate chances of cross-reactivity when amino acid similarity and not just exact sequence is accounted: 89-90% homology to IL-13 from sheep, dolphin, beluga, and bovine, 83-88% to human and certain monkey IL-13, 80-82% to dusky titi, macaque, baboon, mangabey, dog, llama, camel, and galago, 75-78% to horse, and 67-72% to rat, mouse, and gerbil. Cross-reactivity with IL-13 from other sources has not been determined.
交叉反应 绵羊
产品特性 Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ralpha) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. Anti-IL-13 antibody antibody is ideal for investigators involved in Cancer and Immunology research.
纯化方法 purified
过滤 Sterile filtered
免疫原 This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein.
Immunogen Type: RecombinantProtein
亚型 IgG
Plasmids, Primers & others

IL-13目标详情

IL-13抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 IL13 (IL13 Antibody 摘要)
背景 Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. Anti-IL-13 antibody antibody is ideal for investigators involved in Cancer and Immunology research.
Synonyms: Interleukin-13, IL-13
基因ID 396721, 189176151
UniProt B3GDZ5
途径 JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport

使用细节

IL-13抗体详情 IL-13目标详情 贮存及处理 图像 回页首
应用备注 IL-13 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 13.2 kDa in size corresponding to swine IL-13 protein by western blotting in the appropriate cell lysate or extract.
说明

Gene Name: IL-13

限制 仅限研究用

贮存及处理

IL-13抗体详情 IL-13目标详情 使用细节 图像 回页首
状态 Lyophilized
溶解方式 Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
浓度 1.0 mg/mL
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
有效期 12 months

图像

IL-13抗体详情 IL-13目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Interleukin 13 (IL13) antibody (ABIN964711) Western blot using protein-A purified anti-swine IL-13 antibody shows detection of r...