anti-猪 IL-13 抗体 for Enzyme Immunoassay

Recommended IL-13 Antibody

抗原
Interleukin 13 (IL13) 抗体
  • IL13
  • IL-13
  • P600
  • Il-13
  • L13
  • interleukin 13
  • IL13
  • Il13
适用

192
81
54
8
7
3
3
2
2
2
2
1
1
宿主

185
61
45
6
2
克隆类型
多克隆
标记
This IL-13 antibody is un-conjugated
37
13
7
6
4
4
2
2
2
2
2
2
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
195
162
62
37
30
22
20
17
17
13
11
10
10
9
6
4
3
2
2
2
1
1
1
1
选项

Available images

产品编号 ABIN401064
$ 594.00
加上运输费 $45.00

General

抗原 Interleukin 13 (IL13) 抗体
适用
(192), (81), (54), (8), (7), (3), (3), (2), (2), (2), (2), (1), (1)
宿主
(185), (61), (45), (6), (2)
克隆类型
多克隆
标记 This IL-13 antibody is un-conjugated
(37), (13), (7), (6), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
应用范围 Enzyme Immunoassay (EIA), Western Blotting (WB)
(195), (162), (62), (37), (30), (22), (20), (17), (17), (13), (11), (10), (10), (9), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 找到1个引用
Supplier

IL-13抗体详情

IL-13目标详情 使用细节 贮存及处理 References for anti-IL-13 antibody (ABIN401064) 图像
特异性 This antibody reacts to Interleukin-13.
交叉反应 (详细) Species reactivity (expected):Sheep, Dolphin, Beluga, Bovine, Human, Certain monkey, Dusky titi, Macaque, Baboon, Mangabey, Canine, Llama, Camel, Galago, Horse, Rat, Mouse, Gerbil.
Species reactivity (tested):Porcine.
纯化方法 Affinity chromatography on Protein A
免疫原 Full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein
亚型 IgG
Plasmids, Primers & others

IL-13目标详情

IL-13抗体详情 使用细节 贮存及处理 References for anti-IL-13 antibody (ABIN401064) 图像 回页首
抗原
别名 Interleukin-13 / IL13 (IL13 Antibody 摘要)
背景 Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ra) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation.Synonyms: IL-13, NC30
基因ID 396721
NCBI登录号 NP_998968
UniProt Q95J68
途径 JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport

使用细节

IL-13抗体详情 IL-13目标详情 贮存及处理 References for anti-IL-13 antibody (ABIN401064) 图像 回页首
应用备注 ELISA: 1/11,000. Western Blot: 1.5 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

IL-13抗体详情 IL-13目标详情 使用细节 References for anti-IL-13 antibody (ABIN401064) 图像 回页首
状态 Liquid
溶解方式 Restore with 100 μL of deionized water or equivalent.
浓度 1.0 mg/mL by UV absorbance at 280 nm
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IL-13 antibody (ABIN401064)

IL-13抗体详情 IL-13目标详情 使用细节 贮存及处理 图像 回页首
背景

Trigona, Brown, Estes: "Functional implications for signaling via the IL4R/IL13R complex on bovine cells." in: Veterinary immunology and immunopathology, Vol. 72, Issue 1-2, pp. 73-9, 2000

图像

IL-13抗体详情 IL-13目标详情 使用细节 贮存及处理 References for anti-IL-13 antibody (ABIN401064) 回页首
厂商提供的图像
 image for anti-Interleukin 13 (IL13) antibody (ABIN401064) anti-Interleukin 13 (IL13) antibody