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This is the first report of positive association of IFNA (显示 IFNA2 蛋白) gene in SLE, especially the role of specific subtypes IFNA1 (显示 IFNA1 蛋白) and IFNA5.
Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.
Produced by macrophages, IFN-alpha have antiviral protein kinase and an oligoadenylate synthetase.
, interferon alpha-61
, interferon alpha-G
, interferon alpha family, gene 5
, interferon, alpha 5