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抗Human IFNA 抗体:
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抗Rat (Rattus) IFNA 抗体:
Chicken Monoclonal IFNA Primary Antibody for ELISA, WB - ABIN2474115
Sick, Schultz, Staeheli: A family of genes coding for two serologically distinct chicken interferons. in The Journal of biological chemistry 1996
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Mouse (Murine) Monoclonal IFNA Primary Antibody for Func, IA - ABIN2191742
Diebold, Montoya, Unger, Alexopoulou, Roy, Haswell, Al-Shamkhani, Flavell, Borrow, Reis e Sousa: Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. in Nature 2003
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Chicken Polyclonal IFNA Primary Antibody for Func, IP - ABIN2474117
Schultz, Kaspers, Rinderle, Sekellick, Marcus, Staeheli: Recombinant chicken interferon: a potent antiviral agent that lacks intrinsic macrophage activating factor activity. in European journal of immunology 1995
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Human Monoclonal IFNA Primary Antibody for ELISA, Func - ABIN250928
Shearer, Taylor-Papadimitriou, Griffin, Balkwill: Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers. in Journal of immunology (Baltimore, Md. : 1950) 1984
Mouse (Murine) Monoclonal IFNA Primary Antibody for Func, IHC (fro) - ABIN2474118
Wheat: Eimeria Macyi sp. n. (Protozoa: Eimeriidae) from the eastern pipistrelle, Pipistrellus subflavus, from Alabama. in The Journal of parasitology 1976
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Human Monoclonal IFNA Primary Antibody for IHC (fro), ELISA - ABIN2474116
Reed, Vukmanovic-Stejic, Fletcher, Soares, Cook, Orteu, Jackson, Birch, Foster, Salmon, Beverley, Rustin, Akbar: Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo. in The Journal of experimental medicine 2004
the polymorphic variant of IFNA1 (显示 IFNA1 抗体) (-2) gene is associated with chronic HBV infection
Cerebrospinal fluid interferon alpha levels correlate with neurocognitive impairment in ambulatory HIV-Infected individuals.
Data suggest a central role of XBP1 (显示 XBP1 抗体) in TLR7 (显示 TLR7 抗体)-induced IFNalpha production and identify XBP1 (显示 XBP1 抗体) as a potential novel therapeutic target in IFNalpha-driven autoimmune and inflammatory diseases.
Study shows IFN-alpha rapidly induces a profound shift in whole brain network structure, impairing global functional connectivity and the efficiency of parallel information exchange.
The review focuses on the value of the type I and III interferon subtypes (alphas, beta and lambdas) as therapeutics for prevention and treatment of viral infections (influenza, herpes, human immunodeficiency virus and hepatitis viruses).
MiR (显示 MLXIP 抗体)-181a is an important mediator for interferons-induced SAMHD1 (显示 SAMHD1 抗体) expression in astrocytes and microglia, but not for inhibition of HIV-1 infection induced by IFN-alpha.
the expression of certain TAM (显示 CCNA1 抗体) components was reduced as a result of prolonged degradation of MYD88 (显示 MYD88 抗体) by Porphyromonas gingivalis infection.
Type I interferons (IFNs) signature is seen in a significant proportion of anti-nuclear antibody-positive (ANA (显示 BTG3 抗体)(+) individuals and appears to be associated with ANA (显示 BTG3 抗体) titre and type of autoantibodies, rather than with the presence or development of clinical systemic autoimmune rheumatic diseases (SARDs) symptoms.
study found that endogenous IFNalpha autocrinally promotes the expression of Interferon-Stimulated Gene (ISG) mRNAs in IL-3 (显示 IL-3 抗体)-, but not in IFNlambda3 plus IL-3 (显示 IL-3 抗体)-, treated plasmacytoid dendritic cells (pDCs); production of IFNalpha by IFNlambda3 plus IL-3 (显示 IL-3 抗体)-treated pDCs is mostly dependent on endogenously produced TNFalpha (显示 TNF 抗体)
results demonstrate that Sphingosine 1-phosphate lyase (SPL (显示 SGPL1 抗体)) is a host factor that augments type I IFN responses during influenza A virus infection; study delineates the relationship between IKKepsilon (显示 IKBKE 抗体) and SPL (显示 SGPL1 抗体), which provides a mechanistic understanding of the pro-IFN activity of SPL (显示 SGPL1 抗体)
The TBK1 (显示 TBK1 抗体) Y179A mutant failed to rescue type I IFN production by virally infected RAW264.7 macrophages deficient in TBK1 (显示 TBK1 抗体).
this study introduces a novel pathway by which IFN-alpha serves as a proatherogenic mediator through repression of eNOS (显示 NOS3 抗体)-dependent pathways
study reports that mitochondrial antiviral signaling protein (MAVS (显示 MAVS 抗体)), -mediated IFN-alpha/beta production and IFNAR (显示 IFNAR1 抗体) signaling are required for alloimmune responses to the human K1 Ag in a murine model of inflammation-induced alloimmunization
These findings also identify STAT3 (显示 STAT3 抗体) as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha responsiveness.
CD169 (显示 SIGLEC1 抗体)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (显示 CD8A 抗体)(+) T-cell exhaustion and immunopathology.
These results suggest that pulmonary C-fibers affect IFNGR1 (显示 IFNGR1 抗体) expression by inducing IFN-alpha to regulate IFN-gamma (显示 IFNG 抗体)-mediated airway inflammation and airway hyperresponsiveness.
results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (显示 CD8A 抗体)(+) T cell response
the close association between the increased proportion of CD180 (显示 CD180 抗体)-negative B cells and the activation of IFN-alpha signaling in Systemic lupus erythematosus, is reported.
STAT2 (显示 STAT2 抗体) recruits USP18 (显示 USP18 抗体) to the type I IFN receptor subunit IFNAR2 (显示 IFNAR2 抗体) via its constitutive membrane-distal STAT2 (显示 STAT2 抗体)-binding site.
Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon response by inducing STAT1 (显示 STAT1 抗体) degradation.
Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 (显示 IRF3 抗体) and subsequent degradation of IRF-3 (显示 IRF3 抗体), leading to downregulation of IFN-alpha/beta production.
Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29.
Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.
Nsp1beta inhibits interferon-activated (显示 MNDA 抗体) STAT1 (显示 STAT1 抗体)/STAT2 (显示 STAT2 抗体) signal transduction by inducing karyopherin-alpha1 degradation.
Expression of Mx protein (显示 MX2 抗体) and interferon-alpha (IFN-alpha) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.
Foot-and-Mouth Disease Virus inhibits IFN-alpha expression in infected cells by blocking cap-dependent translation.
produced in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus in lymph nodes cells expressing the myeloid markers CD14 (显示 CD14 抗体), CD11b (显示 ITGAM 抗体), and CD172a (显示 SIRPA 抗体)
Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 (显示 STAT1 抗体) and, to a lesser extent, STAT2 (显示 STAT2 抗体).
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted.
, interferon alpha
, interferon alpha 7
, IFN-alpha 1b
, interferon alpha 1b
, interferon alpha-1/13
, interferon alpha-D
, leIF D
, interferon alpha family gene 1
, interferon alpha-1
, interferon alpha 1
, IFN alpha
, interferon type A1/A2
, interferon type A3
, interferon alpha A
, Interferon alpha-1