anti-小鼠 AGT 抗体 for ELISA

Recommended AGT Antibody (supplied by: Log in to see )

抗原
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) 抗体
  • ANHU
  • SERPINA8
  • AI265500
  • AngI
  • AngII
  • Aogen
  • Serpina8
  • ANRT
  • Ang
  • PAT
  • wu:fb62f06
  • wu:fj87b02
  • zgc:111892
  • AGT
  • angt
  • ANGT
  • angiotensinogen
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • AGT
  • Agt
  • agt
抗原表位
AA 1-477
37
16
13
11
8
8
8
5
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
适用
小鼠
225
68
62
8
2
2
2
2
2
2
1
宿主

182
82
2
克隆类型
多克隆
标记
This AGT antibody is un-conjugated
20
14
6
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
ELISA, Western Blotting (WB)
172
104
91
47
24
22
20
14
14
11
6
4
3
2
1
1
1
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产品编号 ABIN2000803
$ 218.90
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN6259830 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2691419 ELISA Rabbit IgG AA 1-477 Log in to see Polyclonal 0
1 ABIN796715 ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN6097868 ELISA IF/ICC IHC WB Rabbit IgG AA 35-285 Log in to see Polyclonal 0
1 ABIN1173619 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN2426559 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2431969 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2430999 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2426561 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2431971 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044526 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044744 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6045122 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6042513 ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044745 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2906739 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5702052 ELISA FACS IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1082946 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2753291 IHC ELISA WB Rabbit IgG AA 35-285 Log in to see Polyclonal 0
1 ABIN5911989 ELISA FACS IHC WB Rabbit IgG Log in to see Polyclonal 0

General

抗原 Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) 抗体
抗原表位 AA 1-477
(37), (16), (13), (11), (8), (8), (8), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 小鼠
(225), (68), (62), (8), (2), (2), (2), (2), (2), (2), (1)
宿主
(182), (82), (2)
克隆类型
多克隆
标记 This AGT antibody is un-conjugated
(20), (14), (6), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 ELISA, Western Blotting (WB)
(172), (104), (91), (47), (24), (22), (20), (14), (14), (11), (6), (4), (3), (2), (1), (1), (1)
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AGT抗体详情

AGT目标详情 使用细节 贮存及处理 图像
特异性 Mouse Angiotensinogen / SerpinA8 / AGT
产品特性 Produced in rabbits immunized with purified, recombinant Mouse Angiotensinogen / SerpinA8 / AGT (rM Angiotensinogen / SerpinA8 / AGT, ABIN2007685 P11859, Met 1-Val 477,. Angiotensinogen / SerpinA8 / AGT specific IgG was purified by Mouse Angiotensinogen / SerpinA8 / AGT affinity chromatography.
纯化方法 purified by affinity chromatography
过滤 0.2 μm filtered
免疫原 Recombinant Mouse Angiotensinogen / SerpinA8 / AGT protein (ABIN2007685)
亚型 IgG
Plasmids, Primers & others

AGT目标详情

AGT抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 AGT (AGT Antibody 摘要)
背景 Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. Angiotensinogen can be schematically considered to consist of a combination of an angiotensin I (Ang I) function, located at the N-terminal end, and the presence of a serpin (serine protease inhibitor) structure at the opposite end. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system. Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD). Several serpins (antithrombin, maspin, pigment epithelial-derived factor, and kallistatin) have been recently shown to exert an antiangiogenic activity, suggesting a common mechanism of endothelial cell proliferation and migration. Angiotensinogen/AGT and its renin-cleaved product, des(Ang I)AGT, are also angiogenesis inhibitors, both in vitro and in vivo at concentrations within the range of those observed in plasma. The Angiotensinogen products, that is angiotensin II and possibly angiotensin II-related products, have been found to act locally in modulating adipose tissue growth in an autocrine/paracrine manner. The transient or chronic overexpression of angiotensinogen in adipose tissue favors lipogenesis in adipocytes and leads to a 'vicious' circle whereby adipose tissue development is further increased.
UniProt P11859
途径 JAK/STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity

使用细节

AGT抗体详情 AGT目标详情 贮存及处理 图像 回页首
应用备注 WB: 5-10 μg/mL
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse AGT. The detection limit for Mouse AGT is approximately 0.00245 ng/well.
限制 仅限研究用

贮存及处理

AGT抗体详情 AGT目标详情 使用细节 图像 回页首
状态 Liquid
缓冲液 0.2 μm filtered solution in PBS with 5 % trehalose
储存液 Without preservative
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 4 °C,-20 °C,-80 °C
储存方法 This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
有效期 12 months

图像

AGT抗体详情 AGT目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 1-477) antibody (ABIN2000803) anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 1-477) antibody