Use your antibodies-online credentials, if available.
Human Polyclonal DDX17 Primary Antibody for ICC, IF - ABIN152386
Jin, Chen, Di, Miron, Hou, Gao, Shao: Estrogen receptor (ER) beta or p53 attenuates ERalpha-mediated transcriptional activation on the BRCA2 promoter. in The Journal of biological chemistry 2008
Show all 3 Pubmed References
Mutant p53 protein (显示 TP53 抗体) (Mutp53) binds and sequesters RNA helicases p72/82 from microprocessor causing an attenuation of microRNAs (miRNAs) maturation.
DDX17 contributes to acquired gefitinib resistance through exportin (显示 XPO1 抗体)/importin-dependent cytoplasmic shuttling and activation of beta-catenin (显示 CTNNB1 抗体) in non-small lung cancer cells.
The miRNA biogenesis factors, DDX17 and KHSRP (显示 KHSRP 抗体), regulate the protein level of Ago2 (显示 EIF2C2 抗体) in human cells.
DDX17 is a Sox2 (显示 SOX2 抗体)-binding protein in estrogen receptor (显示 ESR1 抗体)-positive breast cancer; in reporter responsive (RR) cells but not reporter unresponsive (RU) cells, DDX17 enhances the tumorigenic and stem-like features of Sox2 (显示 SOX2 抗体) by promoting its binding to its target genes
Overexpression of p72 decreased Beclin1 (显示 BECN1 抗体) expression partially by increasing miR (显示 MLXIP 抗体)-34-5p and miR (显示 MLXIP 抗体)-5195-3p expression in glioma cells.
Systematic Determination of Human Cyclin Dependent Kinase (显示 CDK1 抗体) (CDK)-9 (显示 CDK9 抗体) Interactome Identifies Novel Functions in RNA Splicing Mediated by the DDX5 (显示 DDX5 抗体) and DDX17 RNA Helicases
Downregulation of DDX5 (显示 DDX5 抗体) and DDX17 protein expression during myogenesis and epithelial-to-mesenchymal transdifferentiation contributes to the switching of splicing programs during these processes.
Depletion of DDX17 but not the related helicase DDX5 (显示 DDX5 抗体) increased Rift Valley fever virus replication in human cells.
DDX17 promotes the production of HIV-1 infectious particles by modulating HIV-1 RNA metabolism.
Data indicate that transcriptional coregulator ddx5 (显示 DDX5 抗体)/ddx17 RNA helicases can simultaneously regulate the transcriptional activity and alternative splicing of NFAT5 (显示 NFAT5 抗体) transcription factor.
Data show that p72/DDX17 specifically interacts with the miR (显示 MLXIP 抗体)-132 loop sequence and influences the relative ratio of the mature mice miR (显示 MLXIP 抗体)-212/132 miRNAs.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
, DEAD box polypeptide 17
, DEAD box protein p72
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)
, RNA-dependent helicase p72
, probable ATP-dependent RNA helicase DDX17
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
, DEAD box protein 17