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DAB2 抗体

(Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
DAB2 抗体  (AA 1-770) DAB2 抗体  (AA 1-770) DAB2 抗体 (AA 1-770) (ABIN514859)

DAB2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

DAB2 抗体 DAB2 抗体 DAB2 抗体 (ABIN7241126)

DAB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

DAB2 抗体  (AA 31-130) DAB2 抗体  (AA 31-130) DAB2 抗体 (AA 31-130) (ABIN760961)

DAB2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

DAB2 抗体 by 适用

Find DAB2 抗体 for a variety of species such as anti-Human DAB2, anti-Mouse DAB2, anti-Rat DAB2. The species listed below are among those available. Click on a link to go to the corresponding products.

DAB2 抗体 by 应用范围

Find DAB2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

DAB2 抗体 by 抗体来源

Find DAB2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

DAB2 抗体 by 抗原表位

Find DAB2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

DAB2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal DAB2 抗体. Click on a link to go to the corresponding products.

DAB2 抗体 by 克隆

Find DAB2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

DAB2 抗体 by 标记

Find DAB2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular DAB2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN514859
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7241126
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN760961
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652936
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN1386225
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN514860
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN514861
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6261215
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IHC (p)
Validations
  • (1)
Cat. No. ABIN2597796
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881248
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2777076
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5000970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN760963
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1388941
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IF (cc), IF (p), FACS
Validations
Cat. No. ABIN893369
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our DAB2 抗体

Collaco, Jakab, Hegan, Mooseker, Ameen: "Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 17177-87, (2010) (PubMed).

Chaudhury, Hussey, Ray, Jin, Fox, Howe: "TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI." in: Nature cell biology, Vol. 12, Issue 3, pp. 286-93, (2010) (PubMed).

Hasumi, Baba, Ajima, Hasumi, Valera, Klein, Haines, Merino, Hong, Yamaguchi, Schmidt, Linehan: "Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 44, pp. 18722-7, (2009) (PubMed).

Jain, Nguyen, Friedline, Malhotra, Brehm, Koyanagi, Bix, Cooper, Chambers, Kang: "Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4192-6, (2009) (PubMed).

Jiang, Luo, Howe: "Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions." in: Oncogene, Vol. 28, Issue 33, pp. 2999-3007, (2009) (PubMed).

Mishra, Keyel, Hawryluk, Agostinelli, Watkins, Traub: "Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor." in: The EMBO journal, Vol. 21, Issue 18, pp. 4915-26, (2002) (PubMed).

Hocevar, Smine, Xu, Howe: "The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway." in: The EMBO journal, Vol. 20, Issue 11, pp. 2789-801, (2001) (PubMed).

Smith, Capo-chichi, He, Smedberg, Yang, Prowse, Godwin, Hamilton, Xu: "Disabled-2 mediates c-Fos suppression and the cell growth regulatory activity of retinoic acid in embryonic carcinoma cells." in: The Journal of biological chemistry, Vol. 276, Issue 50, pp. 47303-10, (2001) (PubMed).

Xu, Yang, Jackowski, Rock: "Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product." in: The Journal of biological chemistry, Vol. 270, Issue 23, pp. 14184-91, (1995) (PubMed).

Aliases for DAB2 抗体

DAB2, clathrin adaptor protein (DAB2) 抗体
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (dab2) 抗体
Dab, mitogen-responsive phosphoprotein, homolog 2 (dab2) 抗体
DAB2, clathrin adaptor protein (Dab2) 抗体
disabled 2, mitogen-responsive phosphoprotein (Dab2) 抗体
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