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SMAD7 抗体

(SMAD, Mothers Against DPP Homolog 7 (SMAD7))
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
SMAD7 抗体  (AA 1-100) SMAD7 抗体  (AA 1-100) SMAD7 抗体 (AA 1-100) (ABIN670206)

SMAD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

SMAD7 抗体  (AA 160-260) SMAD7 抗体  (AA 160-260) SMAD7 抗体 (AA 160-260) (ABIN517666)

SMAD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated

SMAD7 抗体  (AA 1-100) SMAD7 抗体  (AA 1-100) SMAD7 抗体 (AA 1-100) (ABIN7270356)

SMAD7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

SMAD7 抗体 by 适用

Find SMAD7 抗体 for a variety of species such as anti-Human SMAD7, anti-Rat SMAD7, anti-Mouse SMAD7. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find SMAD7 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SMAD7 抗体 by 抗体来源

Find SMAD7 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SMAD7 抗体 by 抗原表位

Find SMAD7 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SMAD7 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SMAD7 抗体. Click on a link to go to the corresponding products.

SMAD7 抗体 by 克隆

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SMAD7 抗体 by 标记

Find SMAD7 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SMAD7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS
Validations
  • (3)
  • (5)
Cat. No. ABIN670206
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN517666
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7270356
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7259112
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN517661
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3032632
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN517669
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN517667
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7160246
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7242434
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7256046
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN652239
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN6265178
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561725
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6148092
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SMAD7 抗体

Tang, Reissig, Glasmacher, Regen, Wanke, Nikolaev, Gerlach, Popp, Karram, Fantini, Schattenberg, Galle, Neurath, Weigmann, Kurschus, Hövelmeyer, Waisman: "Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis." in: Gastroenterology, Vol. 156, Issue 3, pp. 692-707.e7, (2019) (PubMed).

Yang, Ding, Xu, Chen, Ding: "MicroRNA-15a inhibition protects against hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 3699-3705, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Aparecida-Silva, Borges, Kessler, Dias, Moreira, Kalil, Gutierrez: "Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 25, Issue 3, pp. 240-6, (2016) (PubMed).

Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).

Liu, Shi, Yang, Zhao, Du, Zou, Yu: "Synchronous alteration pattern between serine-threonine kinase receptor-associated protein and Smad7 in pilocarpine-induced rats of epilepsy." in: Synapse (New York, N.Y.), Vol. 68, Issue 6, pp. 275-82, (2014) (PubMed).

Gao, Aqie, Zhu, Chen, Xu, Jiang, Xu: "MG132 ameliorates kidney lesions by inhibiting the degradation of Smad7 in streptozotocin-induced diabetic nephropathy." in: Journal of diabetes research, Vol. 2014, pp. 918396, (2014) (PubMed).

Kayalar, Oztay: "Retinoic acid induced repair in the lung of adult hyperoxic mice, reducing transforming growth factor-β1 (TGF-β1) mediated abnormal alterations." in: Acta histochemica, Vol. 116, Issue 5, pp. 810-9, (2014) (PubMed).

Chang, Wei, Ho, Berry, Jacobs, Chang, Rosen: "A critical role for the mTORC2 pathway in lung fibrosis." in: PLoS ONE, Vol. 9, Issue 8, pp. e106155, (2014) (PubMed).

Singha, Pandeswara, Geng, Lan, Venkatachalam, Saikumar: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." in: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).

Aliases for SMAD7 抗体

SMAD family member 7 (SMAD7) 抗体
SMAD family member 7 (Smad7) 抗体
SMAD family member 7 L homeolog (smad7.L) 抗体
SMAD family member 7 (smad7) 抗体
CRCS3 抗体
MADH7 抗体
Madh7 抗体
madh7 抗体
MADH8 抗体
Smad7a 抗体
Smad10 抗体
wu:fj60c10 抗体
xsmad7 抗体
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