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PIK3C2A 抗体

(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
PIK3C2A 抗体  (AA 172-403) PIK3C2A 抗体  (AA 172-403) PIK3C2A 抗体 (AA 172-403) (ABIN7431707)

PIK3C2A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PIK3C2A 抗体  (AA 1577-1686) PIK3C2A 抗体  (AA 1577-1686) PIK3C2A 抗体 (AA 1577-1686) (ABIN518885)

PIK3C2A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3E7 unconjugated

PIK3C2A 抗体  (C-Term) PIK3C2A 抗体  (C-Term) PIK3C2A 抗体 (C-Term) (ABIN185194)

Verified PIK3C2A 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

PIK3C2A 抗体 by Grade

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PIK3C2A 抗体 by 适用

Find PIK3C2A 抗体 for a variety of species such as anti-Human PIK3C2A, anti-Mouse PIK3C2A, anti-Pig PIK3C2A. The species listed below are among those available. Click on a link to go to the corresponding products.

PIK3C2A 抗体 by 应用范围

Find PIK3C2A 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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PIK3C2A 抗体 by 克隆形成能力

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PIK3C2A 抗体 by 克隆

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PIK3C2A 抗体 by 标记

Find PIK3C2A 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PIK3C2A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7431707
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (4)
Cat. No. ABIN518885
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (3)
Cat. No. ABIN185194
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN6258303
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN790559
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1863045
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN562223
Quantity 50 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5534605
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6389700
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
Cat. No. ABIN7117469
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
Cat. No. ABIN2583701
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
Cat. No. ABIN2583698
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Pig
Application WB
Validations
Cat. No. ABIN6751402
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2583695
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2583699
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PIK3C2A 抗体

Gulluni, Martini, De Santis, Campa, Ghigo, Margaria, Ciraolo, Franco, Ala, Annaratone, Disalvatore, Bertalot, Viale, Noatynska, Compagno, Sigismund, Montemurro, Thelen, Fan, Meraldi, Marchiò, Pece et al.: "Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function. ..." in: Cancer cell, Vol. 32, Issue 4, pp. 444-459.e7, (2017) (PubMed).

Mathew, Skuli, Mucaj, Lee, Zinn, Sathyan, Imtiyaz, Zhang, Davuluri, Rao, Venneti, Lal, Lathia, Rich, Keith, Minn, Simon: "miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. 291-6, (2014) (PubMed).

Arbuckle, Komiyama, Delaney, Coba, Garry, Rosie, Allchorne, Forsyth, Bence, Carlisle, ODell, Mitchell, Fleetwood-Walker, Grant: "The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment." in: EMBO reports, Vol. 11, Issue 6, pp. 473-8, (2010) (PubMed).

Paulhe, Perret, Chap, Iberg, Morand, Racaud-Sultan: "Phosphoinositide 3-kinase C2alpha is activated upon smooth muscle cell migration and regulated by alpha(v)beta(3) integrin engagement." in: Biochemical and biophysical research communications, Vol. 297, Issue 2, pp. 261-6, (2002) (PubMed).

Domin, Gaidarov, Smith, Keen, Waterfield: "The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles." in: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 11943-50, (2000) (PubMed).

Molz, Chen, Hirano, Williams: "Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain." in: The Journal of biological chemistry, Vol. 271, Issue 23, pp. 13892-9, (1996) (PubMed).

Aliases for PIK3C2A 抗体

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (PIK3C2A) 抗体
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (Pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog (pik3c2a.S) 抗体
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (LOC100548137) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (Pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (pik3c2a) 抗体
CPK 抗体
cpk 抗体
Cpk-m 抗体
PI3-K-C2(ALPHA) 抗体
PI3-K-C2A 抗体
pi3-k-c2a 抗体
PI3KC2 抗体
sb:cb156 抗体
si:dkey-24l11.7 抗体
wu:fc02a04 抗体
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