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Dolutegravir (GSK1349572)

InhA, Func 1051375-19-9
产品编号 ABIN3220585
发货至: 中国
  • 应用范围
    Inhibition Assay (InhA), Functional Studies (Func)
    原理
    Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
    产品特性
    Target: Integrase inhibitor
    Receptor: HIV integrase
    纯化方法
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    纯度
    97 % +
    Formula
    C20H18F2N3NaO5
    Solubility
    200 mM in DMSO
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    储存条件
    -20 °C
    储存方法
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    有效期
    24 months
  • 背景
    Microbiology & Virology,Proteases/Proteasome
    分子量
    441.36 g/mol
    CAS-编号
    1051375-19-9
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