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Decernotinib(VX-509)

InhA, Func 944842-54-0
产品编号 ABIN3220509
发货至: 中国
  • 应用范围
    Inhibition Assay (InhA), Functional Studies (Func)
    原理
    Decernotinib(VX-509, VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM, IC50 is 50-170 nM in cellular assays.
    产品特性
    Target: JAK inhibitor
    Receptor: JAK3
    纯化方法
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    纯度
    100 %
    Formula
    C18H19F3N6O
    Solubility
    10 mM in DMSO
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    储存条件
    -20 °C
    储存方法
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    有效期
    24 months
  • 背景
    JAK/STAT Signaling
    分子量
    392.38 g/mol
    CAS-编号
    944842-54-0
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